Ru-Pt conjugate drug could be the future for cancer therapies
Researchers combined cisplatin, an enhancer and a photodynamic therapy (PDT) drug into a single conjugate that had 10 times the efficacy in treating treatment resistant cancer cells.
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Relationships between SLCs and cytotoxic drugs in human cells uncovered
A new systematic investigation on the role of solute carriers could lead to further insights into how the transporters affect the uptake and activity of drugs.
3D visualisation of COVID-19 surface released for researchers
A new 3D model of the surface of the coronavirus COVID-19 has been released, to aid researchers in the development of a treatment.
New optical technique affords unique insight into blood cell development
Scientists in Hong Kong have developed a novel optical technique that facilitates accurate tracking of hemogenic endothelium cells in zebrafish embryos, providing new insights into the mechanisms of blood formation and potential new understanding of diseases such as leukaemia.
How do stem cells repair damage caused by a heart attack?
Researchers exploring how stem cells can be used discovered that cardiopoietic stem cells could repair in tissue in mouse models of heart attacks.
New method to probe molecules could improve spectroscopy techniques
Researchers have developed a highly sensitive technique for probing molecules that they say could enable new applications in the fields of spectroscopy.
Researchers work to create a COVID-19 viral epitope map
The team used data from SARS-CoV to identify possible viral epitopes that vaccines could include to stimulate an immune response.
Novel nanoscale 4D printer could be used for drug research
A novel 4D printer has been created which can combine organic chemistry, surface science and nanolithography to design surfaces with organic or biological molecules for drug research.
Copper ions could be key to blocking cancer metastasis
Researchers have identified that copper ions and their protein transporters, such as Atox1, are key to cancer cell movement and could be targeted by therapies.
Virtual reality could be used to design new drugs, say researchers
Researchers have used virtual reality (VR) to control how drugs bind to their protein targets, which they say could be useful for designing new treatments.
European Patent Office reports increase in life science patent filings in 2019
Last year, the European Patent Office (EPO) saw the number of patents filed in the pharmaceutical and biotechnology sectors rise for the third year in a row.
Novel assay designed to aid malaria drug and vaccine development
Researchers have developed a novel affordable and reproducible assay to study the malaria parasite, using a new cytoplasmic dye, Cell Trace Far-Red (CTFR).
Artificial enzyme catalytic capabilities improved, say researchers
A study has shown that using a particular three-stranded structure can extend the catalytic performance of artificial metalloenzymes.
CRISPR-Cas3 used to combat C. difficile in lab and mice
Researchers have shown that CRISPR-Cas3 can successfully attack C. difficile in vitro and in mice, by causing DNA damage to the pathogen.
Muscle cell atlas developed to aid muscular disease and injury research
Researchers have created a new technical resource atlas which maps the 15 distinct cell types involved in muscle repair for disease and therapy research.
