Vitamin C effective at targeting cancer stem cells
Vitamin C is up to ten times more effective at stopping cancer cell growth than pharmaceuticals such as 2-DG, according to an article published in Oncotarget
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Scandinavian programme launched to produce all human secreted proteins
A new research programme has been launched to produce all the human secreted proteins in mammalian cell factories. The programme aims to facilitate studies of this important class of proteins, which are involved in many human diseases.
Nanoinjection increases survival rate of cells to 90%
How do tumours grow? And how do bacteria transform harmless substances into medical agents? When biophysicists want to understand what is happening in living cells, they have to introduce fluorescent probes or other foreign molecules. There are several ways to overcome the cell wall without causing the cell permanent harm.
New drug lead identified in fight against Tuberculosis
Believed by many to be a relic of past centuries, tuberculosis (TB) causes more deaths than any other infectious disease including HIV/AIDs. In 2015 there were an estimated 10.4 million new cases of TB and 1.4 million deaths from the disease.
Changes in RNA splicing: a new mechanism for genetic risk in schizophrenia
New research has identified sections of DNA associated with altered regulation of gene expression underlying schizophrenia.
Human neurons in mouse brains are more susceptible to Alzheimer’s pathology
Cells behave differently when removed from their environments, just as cells that develop in cultures do not behave like cells in living creatures.
How blood stem cells can be rejuvenated
Our blood stem cells generate around a thousand billion new blood cells every day. But the blood stem cells’ capacity to produce blood changes as we age. This leads to older people being more susceptible to anaemia, lowered immunity and a greater risk of developing certain kinds of blood cancer.
Obesity can reprogram muscle stem cells
Obesity is associated with reduced muscle mass and impaired metabolism. Epigenetic changes that affect the formation of new muscle cells may be a contributing factor, according to new research from Lund University, Sweden.
Deep Learning predicts hematopoietic stem cell development
Autonomous driving, automatic speech recognition, and the game Go: Deep Learning is generating more and more public awareness.
Stem cell ‘marking’ study offers alternative hypothesis of cancer metastasis
Stem cells are among the most energetically activated, migratory and proliferative sub-populations of tumour cells, according to observations by scholars at the Biomedical Research Centre at the University of Salford.
IT system failures in sample management
Successful compound management and biological sample management stand as key enablers within the drug discovery process...
New discovery to identify Huntington’s disease before symptoms appear
Early warning signs of Huntington’s disease have been uncovered in sheep carrying the human HD mutation, leading the way for new insight into this devastating illness, a new study has found.
Brain-machine interfaces: bidirectional communication at last
Since the early seventies, scientists have been developing brain-machine interfaces; the main application being the use of neural prosthesis in paralyzed patients or amputees. A prosthetic limb directly controlled by brain activity can partially recover the lost motor function. This is achieved by decoding neuronal activity recorded with electrodes and…
Pfizer Director of Biostatistics explores adaptive dose-finding designs in oncology early phase trials
Pfizer Director of Biostatistics to deliver key presentation at the 9th Adaptive Designs in Clinical Trials conference in London in April...
New tool developed to help avoid adverse drug reactions
Medicines are an important part of treating and preventing disease in adults and children. The ideal medicine would have no side effects or adverse drug reactions (ADRs) as they are also called, but the reality is all medicines can cause unwanted effects, in some people.
