Very long-chain fatty acids found to block SARS-CoV-2 infection 11 June 2021 | By Victoria Rees (Drug Target Review) Researchers have shown that omega-3 very long-chain polyunsaturated fatty acids can block SARS-CoV-2 and protect lung cells.
Common antidepressant drugs fight cancer in mice, study shows 11 June 2021 | By Victoria Rees (Drug Target Review) Monoamine oxidase inhibitors can block the function of a protein, helping T cells to effectively fight cancer, a study in mice has shown.
New algorithm could make CRISPR gene editing more precise 11 June 2021 | By Victoria Rees (Drug Target Review) Researchers have created an algorithm that can predict the efficiencies of guide RNAs for CRISPR, potentially making it more precise.
Researchers link SARS-CoV-2 PLpro to COVID-19 symptoms 10 June 2021 | By Victoria Rees (Drug Target Review) Researchers have shown that the SARS-CoV-2 PLpro cuts human proteins so could potentially cause a range of COVID-19 symptoms.
New X-ray scanner analyses biopsies and drugs in minutes 10 June 2021 | By Victoria Rees (Drug Target Review) Researchers have created an X-ray scanning machine that shows the shape of an object and its molecular composition.
Nanoparticle platform enables enhanced delivery of gene therapies 10 June 2021 | By Victoria Rees (Drug Target Review) Scientists have created new nanoparticle-based materials that could be used to deliver gene therapies in an adaptable way.
Senolytic drugs reduce COVID-19 symptoms in mice, study shows 9 June 2021 | By Victoria Rees (Drug Target Review) In pre-clinical studies, senolytic drugs were found to reduce inflammation and death from COVID-19 in older mice.
Study shows how novel drug screen can personalise cancer therapy 9 June 2021 | By Victoria Rees (Drug Target Review) A screening method called dynamic BH3 profiling can identify potentially effective combinations of existing drugs for personalised cancer therapy, research has shown.
Molecules from resin combat epileptic seizures in pre-clinical studies 9 June 2021 | By Victoria Rees (Drug Target Review) Drug molecules from pine and spruce trees can affect certain ion channels and had antiseizure effects in pre-clinical studies.
Screening identifies existing drugs as potential COVID-19 therapies 8 June 2021 | By Victoria Rees (Drug Target Review) Scientists have found four clinically approved drugs and nine compounds with the potential to be repurposed as therapeutics for COVID-19.
TEMPOL drug shows promise as antiviral treatment for COVID-19 8 June 2021 | By Victoria Rees (Drug Target Review) The experimental drug TEMPOL has demonstrated antiviral activity against COVID-19 in a pre-clinical study in cell cultures.
Tiny implant cures diabetes in mice without triggering immune response 7 June 2021 | By Victoria Rees (Drug Target Review) Scientists have developed an implant that releases insulin-secreting cells which has shown success at treating diabetes in mice.
Newly identified protein could become target for cancer immunotherapy 7 June 2021 | By Victoria Rees (Drug Target Review) Researchers have found a protein that, when inhibited in mice with cancer, increased the response to immunotherapy.
SARS-CoV-2 “Mexican variant” sequence analysed by researchers 7 June 2021 | By Victoria Rees (Drug Target Review) Analysis of one million SARS-CoV-2 genome sequences has revealed a new variant named T478K, spreading mostly in Mexico.
Broadly neutralising antibodies could form basis of influenza vaccine 4 June 2021 | By Victoria Rees (Drug Target Review) Antibodies produced by B cells against the H1N1 influenza virus can also neutralise other strains, which could be used to developed vaccines.
