‘Reverse vaccinology’ used to create novel HIV treatment 24 July 2019 | By Victoria Rees (Drug Target Review) Researchers have developed a new HIV vaccine which has shown success in monkeys in pre-clinical trial studies.
Study finds fat cells play key role in melanoma metastasis 24 July 2019 | By Victoria Rees (Drug Target Review) Researchers have found that fat cells transfer cytokines to melanoma cells, which transforms them into aggressive tumours, indicating a drug target for the condition.
Method for inhibiting tumour growth enzyme discovered 23 July 2019 | By Victoria Rees (Drug Target Review) A new study has found a novel way to target an enzyme involved in cancer growth, which could inform therapeutics for the condition.
Models should be in social conditions for pre-clinical trials, study finds 23 July 2019 | By Victoria Rees (Drug Target Review) A study has shown that mice and rats become stressed when housed alone, affecting results of pre-clinical trials.
Experimental compound slows blood cancer growth 23 July 2019 | By Victoria Rees (Drug Target Review) Researchers have identified a protein that plays a role in promoting blood cancer and have successfully used a novel compound to inhibit it, reducing tumour growth.
Genes linked to cell survival during sepsis identified 22 July 2019 | By Victoria Rees (Drug Target Review) Researchers have found a set of genes which helps cells survive during sepsis in mice and could inform potential treatments for the condition.
Promising drug developed for ovarian and pancreatic cancers 22 July 2019 | By Drug Target Review An antibody has been developed to block a protein secreted by the cells surrounding ovarian and pancreatic cancer tumours.
Transfer of oncogene in colon cancer cells demonstrated 22 July 2019 | By Drug Target Review A new study has shown that proteins derived from the oncogene, KRAS, can transfer between colon cancer cells.
Omega-6 fatty acid could help fight heart disease 19 July 2019 | By Drug Target Review Scientists have shown that an omega-6 polyunsaturated fatty acid could halt the progression of atherosclerosis, a leading cause of heart disease.
Leukemia stem cells made visible to the immune system 19 July 2019 | By Drug Target Review A new study may provide the basis for combating malignant leukemia stem cells.
Use of animal models decreases by 7 percent 19 July 2019 | By Victoria Rees (Drug Target Review) In figures released by the Home Office, the use of animal models has decreased down to 3.52 million procedures in 2018.
New version of HIV vaccine could soon be ready for clinical trials 18 July 2019 | By Drug Target Review A promising vaccine that clears an HIV-like virus from monkeys is closer to clinical trial human testing.
Study shows p38 protein regulates formation of new blood vessels 18 July 2019 | By Drug Target Review A new study shows that the activity of p38 is important in MSCs, which can localise around blood vessels.
Cause of MS damage in the brain identified 18 July 2019 | By Victoria Rees (Drug Target Review) A study has discovered that the damage of projection neurons in the brain is caused by immune cells, leading to MS.
Little progress shown for gender diversity in major pharma companies 17 July 2019 | By Drug Target Review A new report shows that there is still a lack of female representation within the senior roles of the major pharmaceutical companies.
