‘Reverse vaccinology’ used to create novel HIV treatment
Researchers have developed a new HIV vaccine which has shown success in monkeys in pre-clinical trial studies.
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Study finds fat cells play key role in melanoma metastasis
Researchers have found that fat cells transfer cytokines to melanoma cells, which transforms them into aggressive tumours, indicating a drug target for the condition.
Method for inhibiting tumour growth enzyme discovered
A new study has found a novel way to target an enzyme involved in cancer growth, which could inform therapeutics for the condition.
Models should be in social conditions for pre-clinical trials, study finds
A study has shown that mice and rats become stressed when housed alone, affecting results of pre-clinical trials.
Experimental compound slows blood cancer growth
Researchers have identified a protein that plays a role in promoting blood cancer and have successfully used a novel compound to inhibit it, reducing tumour growth.
Genes linked to cell survival during sepsis identified
Researchers have found a set of genes which helps cells survive during sepsis in mice and could inform potential treatments for the condition.
Promising drug developed for ovarian and pancreatic cancers
An antibody has been developed to block a protein secreted by the cells surrounding ovarian and pancreatic cancer tumours.
Transfer of oncogene in colon cancer cells demonstrated
A new study has shown that proteins derived from the oncogene, KRAS, can transfer between colon cancer cells.
Omega-6 fatty acid could help fight heart disease
Scientists have shown that an omega-6 polyunsaturated fatty acid could halt the progression of atherosclerosis, a leading cause of heart disease.
Leukemia stem cells made visible to the immune system
A new study may provide the basis for combating malignant leukemia stem cells.
Use of animal models decreases by 7 percent
In figures released by the Home Office, the use of animal models has decreased down to 3.52 million procedures in 2018.
New version of HIV vaccine could soon be ready for clinical trials
A promising vaccine that clears an HIV-like virus from monkeys is closer to clinical trial human testing.
Study shows p38 protein regulates formation of new blood vessels
A new study shows that the activity of p38 is important in MSCs, which can localise around blood vessels.
Cause of MS damage in the brain identified
A study has discovered that the damage of projection neurons in the brain is caused by immune cells, leading to MS.
Little progress shown for gender diversity in major pharma companies
A new report shows that there is still a lack of female representation within the senior roles of the major pharmaceutical companies.
