product
ProteinSimple AlphaImager Mini Imaging System
13 December 2015 | By ProteinSimple
AlphaImager Mini is a compact and economical digital imaging system, ideal for routine imaging of fluorescent and colorimetric DNA and protein gels...
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Imaging
news
SRI and Stanford Cancer Institute in ‘first-in-class’ collaboration
10 December 2015 | By Victoria White
SRI Biosciences and physician-researchers from Stanford Cancer Institute (SCI) are to pursue development of novel compounds to treat multiple forms of cancer and other conditions...
news
Takeda and Cour in coeliac disease collaboration
10 December 2015 | By Victoria White
The partnership will focus on using nanotechnologies based on Cour’s Tolerizing Immune Modifying nanoParticle (TIMP) platform...
news
Cypralis collaborates with Janssen on cyclophilin inhibitors
7 December 2015 | By Victoria White
The collaboration, facilitated by Johnson & Johnson Innovation, aims to develop new cyclophilin inhibitors for neurodegenerative diseases...
video
Video: Simple Western Product Overview (Wes, Sally Sue, Peggy Sue and NanoPro 1000)
6 December 2015 | By ProteinSimple
This video provides an overview of the features from the Simple Western product range by ProteinSimple, including Wes, Sally Sue, Peggy Sue or NanoPro 1000...
article
Analysing recombinant proteins by mass spectrometry
The drug discovery landscape is changing: no longer limited to big pharma, it is now within reach of academics and small consortia alike. Regardless of the setting, drug discovery requirements are always the same: strong biological theory, good chemical starting material and high quality protein samples from which to determine…
product
ProteinSimple Ella Simple Plex System
5 December 2015 | By ProteinSimple
Ella runs hands-free, multiplex-free, ELISA-free Simple Plex assays. She’ll give you results for multiple samples in 60 minutes flat...
article
Mass spectrometry and systems biology approaches in drug target discovery
Cells, organs and organisms are complex biological systems consisting of inter-related components that co-operatively work to maintain function and respond to change. Malfunction of any component can lead to pathologies and disease, leading to system-wide changes and subsequent adaptation. Hence, the ability to study and predict system behaviour will considerably…
product
ProteinSimple MFI 5000 Series
4 December 2015 | By ProteinSimple
Address the US FDA requirement to characterize and quantify protein aggregates and other particle contaminants sized 1-70 microns in biotherapeutics...
article
Drug Target Review – Issue #4 2015
3 December 2015 | By Drug Target Review
Included in this issue: Biomarkers, Mass Spectrometry, Target Validation, Drug Development, Personalised Medicines, Next-Generation Sequencing, Protein Expression, Companion Diagnostics, and much more...
article
Mass Spectrometry In-Depth Focus 2015
In this Mass Spectrometry In-Depth Focus: Michelle M. Hill from University of Queensland discusses Mass spectrometric and systems biology approaches in drug target discovery, and Nicola Burgess-Brown, Rod Chalk, Claire Strain-Damerell and Pravin Mahajan from the Structural Genomics Consortium look at analysing recombinant proteins by mass spectrometry...
article
The challenges associated with ‘de-risking’ early-stage therapeutic targets
The pharmaceutical industry is searching for novel drug targets that could produce the next generation of ‘first-in-class’ therapeutic agents. The challenge for academia is to identify and translate such targets and to provide starting points and confidence in the underlying science. The aim should be to generate evidence that modulation…
article
Enabling new targets by integrated lead discovery
Progress in the understanding of disease mechanisms provides new opportunities to discover molecules that modulate disease. To capitalise on these opportunities, successful lead discovery strategies need to build on insights into how a cellular phenotype or a target contributes to disease biology. Recent advances in induced pluripotent stem cells (iPSCs),…
news
Boehringer Ingelheim and MD Anderson in pancreatic cancer collaboration
2 December 2015 | By Victoria White
Boehringer Ingelheim and The University of Texas MD Anderson Cancer Centre are to focus on developing new medicines for pancreatic ductal adenocarcinoma...
product
ProteinSimple NanoPro 1000
2 December 2015 | By ProteinSimple
Simple Western™ system for the characterization of post-translational protein modification by the detection of charge isoforms...
