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The toxicity and antiviral properties of 24 low-molecular-weight artificial RNases (artRNases) including peptides, peptidomimetics, N-alkyl-substituted 1,4-diazabicyclo[2.2.2]octane (DABCO) and a silver (I) complex with cystine were analysed for viruses containing single-stranded and double-stranded genomic RNA (the tick-borne encephalitis virus; TBEV and the influenza virus, respectively) in vitro and in vivo by…
15 June 2016 | By Victoria White, Digital Content Producer
Scientists from The Scripps Research Institute have developed a powerful new method for finding drug candidates that bind to specific proteins...
15 June 2016 | By Victoria White, Digital Content Producer
According to a study, genetic research in large-scale prospective biobank studies can significantly improve the drug development pipeline and reduce costs...
14 June 2016 | By Mandy Parrett, Editorial Assistant
In the face of the enormous costs involved in bringing a drug to market, pharmaceutical companies are increasingly aiming to develop first-in-class treatments to maximise return on this heavy burden, notes intelligence provider, GBI Research.
9 June 2016 | By Victoria White, Digital Content Producer
The Meso-Brain project could revolutionise the understanding of disease and lead to new treatments for those with dementia or brain injuries...
7 June 2016 | By Victoria White, Digital Content Producer
LDC and McGill University are to work together to identify tools to help develop novel endoplasmic reticulum related diseases therapies...
31 May 2016 | By Victoria White, Digital Content Producer
A newly developed contrast agent can improve monitor at the cellular level, which is a crucial element in measuring the efficacy of stem cell treatments...
31 May 2016 | By Charles River
Charles River highlights new kinetic PET imaging and AIF as new tools in our comprehensive portfolio of imaging and associated ex vivo techniques...
3 May 2016 | By Victoria White, Digital Content Producer
Researchers have obtained images of the NMDA receptor in different states. Understanding how NMDA receptors activate is critical in designing new drugs...
28 April 2016 | By Victoria White, Digital Content Producer
Researchers have shown that zinc-oxide nanoparticles can prevent genital herpes virus from entering cells, and help natural immunity to develop...
22 April 2016 | By Victoria White, Digital Content Producer
AstraZeneca has launched an integrated genomics initiative to transform drug discovery and development across its entire research and development pipeline...
22 April 2016 | By SMi Group
SMI Reports (12.04.2016): MedImmune Senior Director for R&D to present keynote address on MED10382 at the 3rd Peptides Conference in London...
13 April 2016 | By Victoria White, Digital Content Producer
The effects of LSD on the human brain have been visualised for the first time and may lead to new treatments for psychiatric disorders...
12 April 2016 | By Caroline Richards, Editor, Drug Target Review
Here, Caroline Richards, Editor of Drug Target Review, discusses the publication and the opportunities available to authors...
21 March 2016 | By Victoria White
The MOZART technique could allow scientists to detect tumours in the skin or see abnormal blood vessels from the early stages of macular degeneration...
