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SOMAscan™ assay: a vital proteomic tool in drug discovery

21 September 2015 | By SomaLogic

The SOMAscan™ assay is a highly multiplexed, sensitive, quantitative and reproducible proteomic tool for discovering biomarkers for drug discovery...

BioTek’s Synergy Neo2 Multi-Mode Microplate Reader

article

The importance of measuring drug target residence times

21 September 2015 | By BioTek

The Synergy Neo2 Multi-Mode Reader is designed to provide high temporal resolution in drug target kinetics applications...

article

Enzymes: Ubiquitin-specific proteases as druggable targets

21 September 2015 | By Anton Simeonov, Mindy Davis (National Institutes of Health)

In much the same way that kinases and phosphatases attach and remove phosphate groups from proteins to modulate their activity, there are a series of enzymes (E1, E2, E3) that add one or more ubiquitins onto a protein, as well as enzymes that remove them (deubiquitinases; DUBs), thereby regulating their…

news

Researchers identify possible ovarian cancer biomarkers

17 September 2015 | By Victoria White

The researchers also determined that the level of biomarkers associated with ovarian cancer does not simply increase or decrease over the course of the disease...

news

Amgen and Xencor enter cancer immunotherapy and inflammation collaboration

17 September 2015 | By Victoria White

The research collaboration brings together Amgen's capabilities in target discovery and protein therapeutics with Xencor's XmAb bispecific technology platform...

news

Dementia Consortium funds project focusing on ALS and FTLD

16 September 2015 | By Victoria White

A team at the International Centre for Genetic Engineering and Biotechnology (ICGEB) will join forces with MRC Technology to take on the project...

news

Auspherix and Domainex expand antibiotics partnership

15 September 2015 | By

Since initiating the project in 2014, significant progress has been made towards the invention of new compounds with activity against both gram-positive and gram-negative bacteria...

webinar

Immunology Screening on the iQue Screener

14 September 2015 | By IntelliCyt

Immunology Screening on the iQue Screener: Assays for Immune-Modulators and Immunotherapy...

news

Transatlantic partnership to develop treatments for pancreatic cancer

14 September 2015 | By Victoria White

The five-year programme will focus on the development of ‘nanomedicine’ in the treatment of pancreatic cancer, for which current treatment options are limited...

news

Cancer Research UK and MedImmune launch biotherapeutics research centre

14 September 2015 | By Victoria White

The new laboratory, opened in Cambridge, will focus on the discovery and development of novel biologic cancer treatments and diagnostics...

news

Researchers discover new group of antibiotics

14 September 2015 | By Victoria White

The potential new antibiotics are unlike contemporary antibiotics because they contain iridium, a silvery-white transition metal...

news

Takeda joins malaria and TB drug discovery consortium, WIPO Re:Search

14 September 2015 | By Victoria White

WIPO Re:Search provides access to the intellectual property of certain pharmaceutical compounds, technologies, know-how and data for R&D activities around TB and malaria...

news

Researchers develop a new computational method to study cancer drug effects

11 September 2015 | By Victoria White

Researchers have developed a new method for studying the targets and effects of cancer drugs using data from discovery mass spectrometry experiments...

news

New technique improves the selectivity of kinase inhibitors

11 September 2015 | By Victoria White

The new technique could cut the potential for side effects and help usher kinase inhibitors past strict regulatory hurdles...

news

Gencia and Takeda to develop novel mitochondrial therapeutics

11 September 2015 | By Victoria White

Gencia and Takeda aim to jointly research and develop two preclinical drug candidates, one each in the areas of inflammation and oncology...

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