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Takeda and Cour in coeliac disease collaboration

10 December 2015 | By Victoria White

The partnership will focus on using nanotechnologies based on Cour’s Tolerizing Immune Modifying nanoParticle (TIMP) platform...

news

Nosopharm joins ENABLE to help combat antibiotic resistance

7 December 2015 | By Victoria White

The €100m ENABLE project aims to identify at least three antibacterial lead molecules with promising antibacterial activity, two antibacterial clinical candidate molecules and to enter at least one compound into preclinical and Phase 1 clinical studies...

news

Cypralis collaborates with Janssen on cyclophilin inhibitors

7 December 2015 | By Victoria White

The collaboration, facilitated by Johnson & Johnson Innovation, aims to develop new cyclophilin inhibitors for neurodegenerative diseases...

news

Nordic Nanovector presents preclinical research with betalutin

7 December 2015 | By Victoria White

Betalutin is the first in a new class of Antibody-Radionuclide-Conjugates (ARC) designed to improve upon and complement current options for the treatment of non-Hodgkin Lymphoma (NHL)...

video

Video: Simple Western Product Overview (Wes, Sally Sue, Peggy Sue and NanoPro 1000)

6 December 2015 | By ProteinSimple

This video provides an overview of the features from the Simple Western product range by ProteinSimple, including Wes, Sally Sue, Peggy Sue or NanoPro 1000...

product

ProteinSimple Ella Simple Plex System

5 December 2015 | By ProteinSimple

Ella runs hands-free, multiplex-free, ELISA-free Simple Plex assays. She’ll give you results for multiple samples in 60 minutes flat...

product

ProteinSimple MFI 5000 Series

4 December 2015 | By ProteinSimple

Address the US FDA requirement to characterize and quantify protein aggregates and other particle contaminants sized 1-70 microns in biotherapeutics...

news

Nanobombs – the future of cancer drug delivery?

3 December 2015 | By Victoria White

Researchers say nanobombs might overcome a biological barrier that has blocked development of agents that work by altering the expression of genes in cancer cells...

article

Drug Target Review – Issue #4 2015

3 December 2015 | By Drug Target Review

Included in this issue: Biomarkers, Mass Spectrometry, Target Validation, Drug Development, Personalised Medicines, Next-Generation Sequencing, Protein Expression, Companion Diagnostics, and much more...

article

Mass Spectrometry In-Depth Focus 2015

3 December 2015 | By Claire Strain-Damerell (Structural Genomics Consortium), Michelle Hill (University of Queensland), Nicola Burgess-Brown (Structural Genomics Consortium), Pravin Mahajan (Structural Genomics Consortium), Rod Chalk (Structural Genomics Consortium)

In this Mass Spectrometry In-Depth Focus: Michelle M. Hill from University of Queensland discusses Mass spectrometric and systems biology approaches in drug target discovery, and Nicola Burgess-Brown, Rod Chalk, Claire Strain-Damerell and Pravin Mahajan from the Structural Genomics Consortium look at analysing recombinant proteins by mass spectrometry...

Biomarkers as molecular footprints for cancer therapy

article

Biomarkers as molecular footprints for cancer therapy: current perspectives and promises

3 December 2015 | By Firoz Anwar (King Abdulaziz University), Mahfoozur Rahman (Sam Higginbottom Institute of Agriculture Technology & Sciences), Sarwar Beg (Panjab University), Vikas Kumar (Sam Higginbottom Institute of Agriculture Technology & Sciences)

Knowledge about cancer biomarkers has increased tremendously and provides clinicians and researchers with valued opportunities to understand the molecular mechanism of cancer, thus applying it to effective, early-stage diagnosis and treatment. Cancer biomarkers include a vast range of biochemical molecules such as nucleic acids, proteins, sugars, lipids, small metabolites, cytogenetic…

The challenges associated with ‘de-risking’ earlystage therapeutic targets

article

The challenges associated with ‘de-risking’ early-stage therapeutic targets

3 December 2015 | By Ahmad Kamal (MRC Technology), Catherine Kettleborough (MRC Technology), Debbie Taylor (MRC Technology), Tim Chapman (MRC Technology)

The pharmaceutical industry is searching for novel drug targets that could produce the next generation of ‘first-in-class’ therapeutic agents. The challenge for academia is to identify and translate such targets and to provide starting points and confidence in the underlying science. The aim should be to generate evidence that modulation…

Enabling new targets by integrated lead discovery

article

Enabling new targets by integrated lead discovery

3 December 2015 | By Sylvain Cottens (Novartis), Ulrich Schopfer (Novartis)

Progress in the understanding of disease mechanisms provides new opportunities to discover molecules that modulate disease. To capitalise on these opportunities, successful lead discovery strategies need to build on insights into how a cellular phenotype or a target contributes to disease biology. Recent advances in induced pluripotent stem cells (iPSCs),…

news

Oncology therapeutic pipeline boasts over 6,000 products

2 December 2015 | By Victoria White

GBI Research states that the majority of oncology therapeutics are in the early stages of the pipeline, with 2,937 at the Preclinical stage and 1,591 at the discovery stage...

news

Boehringer Ingelheim and MD Anderson in pancreatic cancer collaboration

2 December 2015 | By Victoria White

Boehringer Ingelheim and The University of Texas MD Anderson Cancer Centre are to focus on developing new medicines for pancreatic ductal adenocarcinoma...

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