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Neutrophil nanosponges soak up rheumatoid arthritis promoting proteins

3 September 2018 | By Iqra Farooq (Drug Target Review)

The neutrophil nanosponges can absorb and neutralise cytokines which play a role in the development of rheumatoid arthritis...

article

Drug Target Review – Issue 3 2018

3 September 2018 | By Drug Target Review

In this issue: pharmacological targeting of mitochondrial dysfunction in Parkinson’s disease, the evolving role of three dimensional in-vitro cell culture techniques in drug discovery, and NGS: hunting mysterious ‘Dark Matter Genome’ towards rewriting the rules of genetic diseases.

news

Cannabidiol shows sustained effects against depression

3 September 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have found that a single dose of cannabidiol in rats with symptoms of depression was highly effective at eliminating symptoms...

article

The changing face in drug discovery

1 September 2018 | By Pushpanathan Muthuirulan

Over the past decade, pharmaceutical industries have contributed enormously to the discovery of new innovative drugs that have saved countless human lives. Discovering new drugs is a complex team sport that requires an intellectual collaboration across many sectors. These advancements provide powerful tools that arm scientists in the quest for…

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Venoms could be used to treat cancer and autoimmune diseases

31 August 2018 | By Iqra Farooq (Drug Target Review)

Venoms are continually being researched as potential chemicals for medicinal therapeutics to treat autoimmune diseases and diabetes...

news

Scientists discover compound for a non-addictive painkiller

30 August 2018 | By Iqra Farooq (Drug Target Review)

Scientists have discovered the chemical compound AT-121, which could soon lead to a painkiller stronger than morphine, but without the side effects...

news

Potential drug to cure ciliopathies

30 August 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have identified a potential treatment that will be a foundation for developing drugs for various genetic disorders...

news

Experimental drug targets cancers associated with Epstein-Barr virus

23 August 2018 | By Iqra Farooq (Drug Target Review)

An experimental drug is reported to have potential to treat Epstein-Barr virus related lymphomas by counteracting the cancer-promoting mechanisms of LMP2A...

news

Modified-RNA vaccine elicits protective response against influenza

22 August 2018 | By Dr Zara Kassam (Drug Target Review)

A universal flu vaccine that protects people against most influenza strains is one step closer to reality...

news

Researchers develop biosensor with real-time oxygen monitoring

21 August 2018 | By Iqra Farooq (Drug Target Review)

In a study, researchers have developed a biosensor concept using organs-on-a-chip to measure the levels of oxygen in real-time...

news

Vitamin B3 could potentially treat kidney injury

21 August 2018 | By Drug Target Review

A team of researchers have identified vitamin B3 can increase levels of NAD+, which is decreased in those with acute kidney injury...

news

Compound with selectivity for cancer cells without p53 identified

20 August 2018 | By Iqra Farooq (Drug Target Review)

The compound has been shown to target cancer cells without the p53 gene, and does not affect healthy cells...

news

GC4419 could prevent debilitating side effect of cancer treatment

20 August 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers are reporting on a new drug that can treat the painful and debilitating side effect of severe oral mucositis (SOM)...

news

Chemical that can kill glioblastoma cells identified

17 August 2018 | By Iqra Farooq (Drug Target Review)

"As an experimental chemical, further rigorous testing and refinement of KHS101 is required before trials in people can begin.”

news

New lead for Alzheimer’s research proposed

15 August 2018 | By Drug Target Review

Researchers identified a connection between the way neurons handle iron and mutations that may cause inherited Alzheimer's disease...

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