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Brochure: Neuroscience solutions

9 June 2021 | By PerkinElmer

Complete solutions for neurological disease research and discovery - helping you to better understand diseases to improve patient outcomes.

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Senolytic drugs reduce COVID-19 symptoms in mice, study shows

9 June 2021 | By Victoria Rees (Drug Target Review)

In pre-clinical studies, senolytic drugs were found to reduce inflammation and death from COVID-19 in older mice.

news

Molecules from resin combat epileptic seizures in pre-clinical studies

9 June 2021 | By Victoria Rees (Drug Target Review)

Drug molecules from pine and spruce trees can affect certain ion channels and had antiseizure effects in pre-clinical studies.

news

Screening identifies existing drugs as potential COVID-19 therapies

8 June 2021 | By Victoria Rees (Drug Target Review)

Scientists have found four clinically approved drugs and nine compounds with the potential to be repurposed as therapeutics for COVID-19.

news

TEMPOL drug shows promise as antiviral treatment for COVID-19

8 June 2021 | By Victoria Rees (Drug Target Review)

The experimental drug TEMPOL has demonstrated antiviral activity against COVID-19 in a pre-clinical study in cell cultures.

whitepaper

ebook: How automation makes labs more efficient

4 June 2021 | By SPT Labtech

We discuss how liquid handling automation supports drug discovery workflows & highlight opportunities to improve the efficiency and quality of these.

Screening reveals antivirals for henipavirus

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High-throughput screening platform detects henipavirus antivirals

3 June 2021 | By Victoria Rees (Drug Target Review)

A new high-throughput screening platform has been used to identify two compounds with antiviral activity against the Nipah and Hendra viruses.

news

Analogue of psychedelic ibogaine reverses effects of stress in mice

26 May 2021 | By Victoria Rees (Drug Target Review)

Tabernanthalog (TBG), similar to the psychedelic drug ibogaine, corrected stress-induced behavioural deficits in mice.

news

Researchers synthesise potential anticancer compounds

26 May 2021 | By Victoria Rees (Drug Target Review)

Scientists have developed six new derivatives of 4-chloro-1,2-dithiol-3-thione, which have all demonstrated anticancer effects in pre-clinical studies.

news

Potential SARS-CoV-2 antiviral to be tested in human lung cells

24 May 2021 | By Victoria Rees (Drug Target Review)

A synthetic antiviral named R327 has shown promise in initial tests against SARS-CoV-2 and is now advancing to the next stage of in vitro studies.

news

High-throughput screening assay developed to discover antimalarials

21 May 2021 | By Victoria Rees (Drug Target Review)

A new assay has been developed to screen for small molecule inhibitors of the Rh5 protein, which is essential for malaria parasite survival.

article

Millennia in the making: unlocking the medicinal value of CBD

20 May 2021 | By Dr Sotirios Karathanasis (Enveda Biosciences)

Dr Sotirios Karathanasis discusses the history of cannabis as a treatment and delves into the process of turning plant-based medicines into clinically proven drugs.

news

Potential COVID-19 antiviral formulated with siRNA-nanoparticles

19 May 2021 | By Victoria Rees (Drug Target Review)

Scientists have created an antiviral therapy using lipid nanoparticles that deliver siRNA to the lungs to treat COVID-19 in mice.

news

Novel inhibitor blocks myeloma cancer cell growth in mouse model

18 May 2021 | By Victoria Rees (Drug Target Review)

Having identified the histone demethylase KDM5A as a multiple myeloma target, researchers developed a KDM5 inhibitor to treat the cancer.

news

Scientists design new drug compound to combat malaria

12 May 2021 | By Victoria Rees (Drug Target Review)

Researchers have developed a set of compounds designed to stop the malaria parasite being able to burst out of red blood cells and replicate.

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