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Novel model developed to resemble aberrant IPF lung epithelium
A new model that closely resembles aged lung epithelium in idiopathic pulmonary fibrosis has been developed, possibly leading to treatments.
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Idiopathic pulmonary fibrosis (IPF)
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Lung fibrosis in mice successfully reversed by scientists
A team of researchers have reversed lung fibrosis in a mouse model, highlighting a new therapeutic target for pulmonary fibrosis.
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Novel target for pulmonary fibrosis identified using tissue from COVID-19 patients
Study suggests reducing the expression of the methyl-CpG-binding domain 2 (MBD2) protein on macrophages could be a viable therapeutic strategy for lung fibrosis.
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Using genetics to identify drug targets for fibrotic lung diseases
Researchers recently conducted a genome-wide association study (GWAS) to identify factors that increase susceptibility to the incurable lung condition idiopathic pulmonary fibrosis (IPF). Here, Dr Richard Allen shares some of the study’s key findings.
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Machine learning could improve tissue model purity
An innovation using artificial intelligence to analyse developing lung cell developments in vitro revealed what promotes them to develop and allowed researchers to create better quality lung tissue models.
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New therapeutic target identified for pulmonary fibrosis
A genetic mutation that causes idiopathic pulmonary fibrosis has been identified and could lead to a new therapeutic approach to treating the disease.
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Possible target found for idiopathic pulmonary fibrosis treatment
A new study shows that using therapeutic antibodies to block the interleukin-11 protein can reverse idiopathic pulmonary fibrosis.
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Mouse models’ mimic lung disease
Researchers have finally been able to mimic IPF in mouse models - a debilitating disease, with no proper treatment and no cure...
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Novel curative gene therapy treatment for pulmonary fibrosis in mice
Researchers in Spain have developed a method of gene therapy that cures pulmonary fibrosis in mice by lengthening telomeres – the protective protein sections at the end of chromosomes.
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Molecular pathway offers treatment targets for pulmonary fibrosis
A study has identified a molecular pathway that appears to be critical to the development of fibrosis...
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Antibody is effective against radiation-induced pulmonary fibrosis
Radiation therapy is part of the treatment regimen for about two thirds of cancer patients today. Radiotherapy is well tolerated in most cases, but it can also lead to damage in healthy tissues that are also irradiated. One debilitating side effect is radiation-induced fibrosis. Fibrosis is a process of scarring…
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New lung ‘organoids’ in a dish mimic features of full-size lung
'Mini organs' may aid in understanding and treating respiratory diseases.
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AdAlta announces IPO to accelerate development of AD-114
8 July 2016 | By Victoria White, Digital Content Producer
AdAlta is seeking to raise up to AU$10 million to fund clinical studies with its lead compound (AD-114) which shows promise in treating lung fibrosis...
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Boehringer Ingelheim and Inventiva enter IPF collaboration
31 May 2016 | By Victoria White, Digital Content Producer
Boehringer Ingelheim and Inventiva have entered a research and drug discovery collaboration with the aim of discovering new IPF treatments...
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MRC Technology launches respiratory ‘Call for Targets’
2 March 2015 | By MRC Technology
Project focused on potential small molecule or antibody targets in pathways important in the development or progression of respiratory disease...
