New research by US institutions in pigs shows that knocking down a particular signalling pathway after heart failure renews heart tissue.
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A group of researchers has found a drug candidate named TRV027 that can increase the cardiac contractility of neonatal mice.
Research determined macrophages’ role in forming a permanent cardiac scar after a heart attack, the researchers suggest altering this behaviour may make the scar temporary and allow restoration of heart function.
A new study has shown that restoring the amount of the kinase, HIPK2, in a kinase-depleted mouse model rescued it from heart failure and identifies HIPK2 as a novel regulator of heart failure progression.
A combination of heart cells derived from human stem cells could lead to developing a treatment for heart failure.
A biomarker has been discovered for the most common type of heart failure - heart failure with preserved ejection fraction...
A team of researchers have demonstrated a new way to sequence proteins that are much more sensitive than existing technology, identifying individual protein molecules rather than requiring millions of molecules at a time
A 3D map of genetic interactions in CVD could aid researchers investigating future treatments for heat attacks, heart failure and heart rhythm disorders.
Researchers are now able to use induced pluripotent stem cells to form a model of human adult-like cardiac muscle...
Reducing a protein found in the mitochondria of cardiac muscle cells initiates cardiac dysfunction and heart failure...
In the gut of patients with heart failure, important groups of bacteria are found less frequently and the gut flora is not as diverse as in healthy individuals.
Researchers in Japan have identified a receptor protein on the surface of heart cells that promotes chronic heart failure.