news Scientists create organoid biobank to study SARS-CoV-2 genes 20 September 2021 | By Anna Begley (Drug Target Review) Researchers have established an organoid biobank to search for genes that are essential for the spreading of SARS-CoV-2 infection.
news New screening method identifies COVID-19 protein inhibitor 3 September 2021 | By Anna Begley (Drug Target Review) Researchers use fast and cost-effective technology to identify the viral protein inhibitor Mpro as a potential drug against COVID-19.
news Innovative algorithm could help advance single-cell genomics 1 September 2021 | By Anna Begley (Drug Target Review) Researchers have developed a novel algorithm, “scArches”, that can compare data on single-cell genomics to better understand diseases.
news Study suggests how to develop intranasal vaccines for COVID-19 and flu 30 August 2021 | By Anna Begley (Drug Target Review) New research has explored the role of nasal bacteria to better develop intranasal vaccines for viruses such as COVID-19 and flu.
news Spike gene mutants could be used as novel COVID-19 vaccine 27 August 2021 | By Anna Begley (Drug Target Review) SARS-CoV-2 Spike gene mutants may be developed into immunogens for new vaccines against COVID-19, a study in hamsters has shown.
news Intranasal COVID-19 vaccine shown to be effective in animal models 26 August 2021 | By Anna Begley (Drug Target Review) A nasal spray of the COVID-19 Vaccine Oxford/AstraZeneca was found to protect hamsters and monkeys against SARS-CoV-2 in an NIH study.
video Drug Target Review update: exclusive report, online summit and more! 25 August 2021 | By Drug Target Review Hear about the latest Drug Target Review updates from Deputy Editor Victoria Rees who discusses our new report on AI & Informatics, the Cell & Gene Therapy Advancements online summit and much more!
news AI method reveals 17 existing drugs that may fight against COVID-19 24 August 2021 | By Anna Begley (Drug Target Review) Scientists used artificial intelligence to identify 17 existing drugs that could kill SARS-CoV-2 in cells, including a dietary supplement.
news Scientists discover new clue for platelet activation to target thrombosis 23 August 2021 | By Anna Begley (Drug Target Review) Researchers have revealed a novel mechanism for platelet activation, suggesting a potential target for antithrombotic therapy.
news Researchers discover glycan “gateway” that enables COVID-19 infection 20 August 2021 | By Anna Begley (Drug Target Review) A supercomputing method has revealed details of glycan “gates” on the SARS-CoV-2 Spike protein that open to allow virus entry and infection.
news CureVac and GSK COVID-19 vaccine shows promise in pre-clinical study 17 August 2021 | By Anna Begley (Drug Target Review) CureVac and GSK's second-generation mRNA COVID-19 vaccine candidate, CV2CoV, demonstrated improved immune response in a pre-clinical study.
news Enzyme discovery could fight against cancer and viral infections 17 August 2021 | By Anna Begley (Drug Target Review) A new study has identified a vital enzyme, known as APOBEC3A, that could lead to new treatments against cancers and viral infections.
news Licensed drug may reduce COVID-19 infection by 70 percent 6 August 2021 | By Anna Begley (Drug Target Review) Fenofibrate and its active form, fenofibric acid, have been shown to significantly reduce COVID-19 infection in human cells.
news Artificial intelligence may reveal how microbiome affects vaccine response 6 August 2021 | By Anna Begley (Drug Target Review) Researchers have been using artificial intelligence to study how the microbiome interacts with the human system to improve vaccine response.
article New models for intranasal drug delivery 6 August 2021 | By Dr Jon Lenn (MedPharm), Dr Jon Volmer (MedPharm) In this article, Dr Jon Volmer and Dr Jon Lenn discuss a new approach to formulation models to test drug delivery based on reconstituted nasal epithelium.