Article: Tips for successful editing in T cells
Horizon article on the recipe for success for CRISPR editing in T cells.
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Whitepapers
Article: Common CRISPR pitfalls and how to avoid them
This article explains how to plan a gene-editing experiment. How to choose your biological system and what reagents to get for your experimental aim.
Application note: Validated quantitation and activity assay of antibody fragment molecule (Fab) for process development and quality control
This application note by ForteBio explores antibody fragment molecule (Fab) for process development and quality control.
Application note: Human iPS cells modified with Edit-R™ CRISPR-Cas9 reagents
Modify the genome and modulate expression of genes within human iPS cells with Dharmacon™ Edit-R CRISPR reagents.
Guide: Navigating hit prioritisation using biochemical assays
So you have performed your screen. What’s next? This guide is focused on how biochemical assays are used for characterising and prioritising compounds.
ebook: A clear and easy guide to Luminex® multiplex immunoassays
Multiplexing allows multiple biological target analytes to be simultaneously examined and quantified in a single sample. It’s a technique widely used by scientific researchers of all disciplines and provides many benefits.
Application note: The effect of column hardware on the analysis of synthetic oligonucleotides by LC-MS
Therapeutic oligonucleotides represent a recent breakthrough in the pharmaceutical industry.
Application note: Effect of temperature on single stranded oligonucleotide analysis
Therapeutic oligonucleotides represent a recent breakthrough in the pharmaceutical industry. However, characterisation of oligos, specifically by ion-pair reversed phase liquid chromatography (IPRPLC), can be quite challenging.
Application note: Effect of perfluorinated alcohols in impurity analysis for synthetic oligonucleotides
Therapeutic oligonucleotides represent a recent breakthrough in the pharmaceutical industry.
Application note: Effect of alkylamine based Ion-pairing reagents in analysis of siRNA
Silencing RNA, or siRNA, are short, double-stranded RNA molecules which are not only an important research tool in molecular biology, but also an emerging therapeutic modality.
Application note: Comparison of fully porous and superficially porous particles for the analysis of synthetic oligonucleotides
Superficially porous particle technologies provide a reduced diffusion path in comparison with their fully porous counterparts minimising the resistance to mass transfer during chromatographic separation.
Whitepaper: Big data and connected tools
As more of the small devices in the lab become connected, more laboratory workflows will be observable, and variability will be better understood.
Case Study: Lab digitalisation and interoperability
Learn how one lab is saving time, improving traceability, and standardising protocols by using connected tools and recording all workflows digitally.
Interview: Stefan Braam, CEO & Founder of Ncardia
Mass production with iPSCs: how Ncardia has pushed the boundaries with high-throughput iPSC research.
Whitepaper: Neuroinflammation study
Neuroinflammation study by combining human iPSC-derived astrocytes and HTRF.
