Application note: See what’s really in your formulation with backgrounded membrane imaging 3SHARES Share via Pinterest Reddit Buffer Xing WhatsApp Flipboard Posted: 18 February 2020 | Halo Labs | No comments yet Backgrounded Membrane Imaging (BMI), used by the HORIZON® particle analysis system, performs measurements of subvisible protein aggregates. When studying the impact of protein aggregate refractive index, IgG protein aggregates analysed on both the HORIZON® instrument and flow imager systems produced equivalent particle count trends. However, the HORIZON® system was more sensitive (measured more overall counts) and had overall lower variability with average CVs of 14.4 percent compared to the flow imager which produced average CVs of 20.1 percent. The differences in variability and counts were most pronounced at lower concentrations and size range respectively. To read this application note in full, please complete the form below. By clicking submit you confirm that you accept our terms and conditions and privacy policy. First Name * Surname * Job Title * Organisation * Town/City * Country * Email * Telephone * * This content is provided to you for free thanks to the kind support of our sponsors: Halo Labs I am happy for my details to be shared with the sponsor(s) of this content *—Please choose an option—YesNo Related content from this organisation Brochure: Particle analysis re-imagined with the Aura™ On-demand webinar: Protein or not? Advanced high throughput aggregate analysis Application note: See what’s really in your formulation with backgrounded membrane imaging Application note: Low volume, high-throughput subvisible AAV aggregate analysis with Horizon Halo Labs Related topicsHit-to-Lead, Imaging, Screening, Stem Cells, Targets Related organisationsHalo Labs
