LifeArc and the Medical Research Council have funded a new drug screening facility that will be established to accelerate COVID-19 drug discovery.
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Discover how workflows are being accelerated to speed up the vaccine research and development process while maintaining safety and immunogenicity.
Computational drug screening has shown that chemotherapy drug pralatrexate could potentially be repurposed to treat COVID-19.
Dr Isaac Karimi and his team explain how compounds to treat COVID-19 could be found in Kurdish ethnomedicine, selecting some plants for computational drug discovery.
When it comes to developing antibody drugs, Dr Jerome Boyd-Kirkup and his team are not sticking to the classical playbook. Here, he explains how they use systems biology and immuno-engineering to remove the element of luck from biologic drug discovery and development.
A new study shows that methacycline, a commonly used antibiotic, can reduce the neurological damage caused by Zika virus infections in mice.
Researchers have found a compound that can prevent up-regulation of CD14, a key inflammatory protein, in cells.
Identify therapeutic effects and adverse responses to compounds earlier in the drug discovery process.
Combining 2D and 3D models with live-cell assays allows monitoring of cell responses in real time and provides important insights about compound treatment effects, biological complexity, and physiological relevance of assay results.
Learn how to perform complex analysis of calcium oscillations and assess cellular and mitochondrial toxicity.
Using hit-to-lead processes, researchers have discovered that KSP inhibitors prevent tumour growth and prolong survival in mice with neuroblastoma.
Scientists used high throughput screening (HTS) to identify molecules that protect against cellular stress in murine skin cells.
A group of scientists has created a novel high-throughput hit-to-lead development platform to identify engineered antibacterial lysins.
Researchers have screened small molecule libraries and then applied hit-to-lead approaches to discover effective vaccine adjuvants.