whitepaper

Application note: Real-time detection of Gs and Gi Signalling in living cells

Posted: 20 June 2018 | | No comments yet

Genetically-encoded biosensors from Montana Molecular allow for detection of GPCR signalling…

G-protein coupled receptors (GPCRs) are predominant drug targets. Therefore, monitoring GPCR activity upon compound addition in a cellular context is required. To this end, Montana Molecular developed biosensors that detect G-protein-driven cAMP generation. The sensor consists of a specific cAMP binding domain and a fluorescent label. It changes its fluorescence intensity if the second messenger cAMP is bound.

    To read this Application Note in full, please complete the form below. By clicking submit you confirm that you accept our terms and conditions and privacy policy.


    *


    *


    *


    *


    *


    *


    *


    *

    This content is provided to you for free thanks to the kind support of our sponsor: BMG Labtech

    I am happy for my details to be shared with the sponsors

    The rest of this content is restricted - login or subscribe free to access

    DTR Issue 3 2021 MiniMagThank you for visiting our website. To access this content in full you'll need to login. It's completely free to subscribe, and in less than a minute you can continue reading. If you've already subscribed, great - just login.

    Why subscribe? Join our growing community of thousands of industry professionals and gain access to:

    • quarterly issues in print and/or digital format
    • case studies, whitepapers, webinars and industry-leading content
    • breaking news and features
    • our extensive online archive of thousands of articles and years of past issues
    • ...And it's all free!

    Click here to Subscribe today Login here

     


    Related organisations