whitepaper

Whitepaper: InCELL target engagement assays

Posted: 6 October 2016 | | No comments yet

Monitoring cellular drug penetration and drug-target interaction enables assessment of compound efficacy and confirmation of mode of action…

Monitoring cellular drug penetration and drug-target interaction enables assessment of compound efficacy and confirmation of mode of action. InCELL Hunter™ and InCELL Pulse™ cellular compound target engagement assays provide the ability to confirm compound cell entry and target binding.

In addition, these assays are designed for screening inhibitors, validating hits identified in biochemical assays, measuring cellular EC50 values, and ranking compounds all in the native cellular environment. These simple binding assays require no custom chemical tracer or antibody reagents and provide a convenient solution when functional assays are difficult or unavailable.

This whitepaper is restricted - login or subscribe free to access

DTR Issue 3 2021 MiniMagThank you for visiting our website. To access this content in full you'll need to login. It's completely free to subscribe, and in less than a minute you can continue reading. If you've already subscribed, great - just login.

Why subscribe? Join our growing community of thousands of industry professionals and gain access to:

  • quarterly issues in print and/or digital format
  • case studies, whitepapers, webinars and industry-leading content
  • breaking news and features
  • our extensive online archive of thousands of articles and years of past issues
  • ...And it's all free!

Click here to Subscribe today Login here

 


Related topics

Related organisations