Webinar: Survey of Today’s Chemical Compound Libraries
ON-DEMAND By Charles River
This webinar discusses the gap between the compound profile of the industry’s current libraries and that of successful drugs approved in recent years...
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Webinars
Biased ligands in Drug Discovery – the case of TRV027
ON-DEMAND By Cisbio Bioassays & Trevena, Inc.
TRV027 is a biased ligand; the in vitro profile and its translation into in vivo pharmacology is discussed during this webinar.
Simultaneous detection of GPCR second messengers in living cells
ON-DEMAND By BMG Labtech GmbH
Due to their role in signal transmission from the outside to the inside of a cell, G-protein coupled receptors (GPCRs) are prominent drug targets.
The kinetics of drug binding
ON-DEMAND By BMG Labtech GmbH
Optimising the receptor binding kinetics of new drugs can have significant benefits, ranging from improved duration of action to enhanced efficacy through the insurmountable antagonism of dynamic physiological systems.Despite this, the kinetics of new receptor ligands are rarely measured early in the drug discovery process, largely because current assays are…