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ON-DEMAND By Charles River
The evolution of tools to analyze motor deficits in animal models and how Charles River is working to support the discovery of new Parkinson’s therapies...
ON-DEMAND By Cisbio Bioassays & Trevena, Inc.
TRV027 is a biased ligand; the in vitro profile and its translation into in vivo pharmacology is discussed during this webinar.
ON-DEMAND By BMG Labtech GmbH
Due to their role in signal transmission from the outside to the inside of a cell, G-protein coupled receptors (GPCRs) are prominent drug targets.
ON-DEMAND By BMG Labtech GmbH
Optimising the receptor binding kinetics of new drugs can have significant benefits, ranging from improved duration of action to enhanced efficacy through the insurmountable antagonism of dynamic physiological systems.Despite this, the kinetics of new receptor ligands are rarely measured early in the drug discovery process, largely because current assays are…
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