Targets

Protein decoy hinders progress of lung cancer growth in mice

14 November 2019 | By Rachael Harper (Drug Target Review)

Researchers have slowed the spread of a type of non-small cell lung cancer in mice by neutralising a protein that would otherwise cause tumour growth.

Potential target found for tuberous sclerosis complex

14 November 2019 | By Rachael Harper (Drug Target Review)

A study on tuberous sclerosis complex has expanded the knowledge of the formation of this disease and how it can be targeted at the molecular level.

Application note: Multiplex Fluorescent Western Blot Detection

13 November 2019 | By Analytik Jena

Challenge: One touch imaging of multiple proteins on the same blot with NIR fluorescent tags. Solution? Automated imaging with the UVP ChemStudio.

eBook: Simple as a Selfie: One-Button Scientific Imaging

13 November 2019 | By Analytik Jena

Proper signal visualization, detection, and quantification are paramount to the acquisition of accurate and reproducible data...

Modified CRISPR gene editing tool could improve therapies

12 November 2019 | By Rachael Harper (Drug Target Review)

New cell experiments show more effective genetic 'cuts' that could one day become the foundation of more effective gene therapies.

Application note: In Vivo Imaging with GFP

12 November 2019 | By Analytik Jena

Challenge: Non-invasive imaging of a patient-derived orthotropic mouse model of pancreatic cancer expressing GFP. The solution? In vivo imaging.

eBook – Getting the Inside Story: In Vivo Imaging

12 November 2019 | By Analytik Jena

In vivo imaging has been an indispensable and powerful tool in biomedical research, enabling a number of significant breakthrough discoveries.

Analytik Jena

Potential new target found for inflammatory disease treatment

8 November 2019 | By Rachael Harper (Drug Target Review)

Molecules made by immune cells to transport sodium lactate could be a target for treatment to stop the lactate build-up in chronic inflammatory disorders.

Regeneration mechanism could provide target for liver disease drugs

6 November 2019 | By Rachael Harper (Drug Target Review)

A newly-discovered molecular mechanism that allows damaged adult liver cells to regenerate could pave the way for drugs for chronic liver diseases.

Novel material for regenerative medicine can control cell immune response

6 November 2019 | By Victoria Rees (Drug Target Review)

Researchers have created a material that can manipulate the immune response and be used as a regenerative medicine therapy.

MaveDB: database to aid research into genetic causes of disease

5 November 2019 | By Drug Target Review

Researchers in Australia and the US have launched the first open-source database detailing genetic variants that impact human health and disease.

RhoA protein function identified in nerve cell development

4 November 2019 | By Drug Target Review

A recent study has revealed new findings about nerve cell development that could help to facilitate future treatment options for spinal cord injuries.

Kinase identified as potential target for heart failure treatment

1 November 2019 | By Rachael Harper (Drug Target Review)

A new study has shown that restoring the amount of the kinase, HIPK2, in a kinase-depleted mouse model rescued it from heart failure and identifies HIPK2 as a novel regulator of heart failure progression.

Potential new target identified for the treatment of gout

30 October 2019 | By Rachael Harper (Drug Target Review)

A new therapeutic target for gout has been identified which could lead to new treatment strategies that could improve the quality of life for patients who suffer from the condition.