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Stem Cells

Stem cells are undifferentiated biological cells that can differentiate into specialised cells and can divide to produce more stem cells.

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Application Note: Full-length, single-cell RNA-seq with the SMARTer™ ICELL8® Single-Cell System

6 September 2018 | By Takara Bio

The data presented in this application note demonstrates how SMARTer ICELL8 Single-Cell System can be used to generate high-quality RNA-seq libraries that provide full-length transcript sequence information from hundreds of single cells in parallel...

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Eppendorf

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Intervertebral disc degeneration could be treated using mesenchymal stem cells

5 September 2018 | By Iqra Farooq (Drug Target Review)

Researchers explored how mesenchymal stem cells could help to treat intervertebral disc degeneration by accelerating disc matrix remodelling...

news

3D liver tissue made from stem cells show promising support of liver function

5 September 2018 | By Drug Target Review

Stem cells transformed into 3D human liver tissue by scientists show promising support of liver function when implanted into mice with a liver disease...

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Matcha green tea kills cancer stem cells

31 August 2018 | By Iqra Farooq (Drug Target Review)

Researchers have found that Matcha green tea has properties to combat breast cancer stem cells...

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New stem cell model to test treatments for neurodegenerative disorders

2 August 2018 | By Drug Target Review

The team found that astrocytes inhibit growth of precursor cells that become myelin, and speed up the neural network in the brain...

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UBR5 protein may reduce neurodegeneration in Huntington’s disease

27 July 2018 | By Dr Zara Kassam (Drug Target Review)

Scientists have made an important step towards understanding the mechanisms that cause the neurodegenerative disorder Huntington's disease...

article

From fibroblasts to medicinal signalling cells: a paradigm shift in translational stem cell research

20 July 2018 | By Darius Widera, Jonathan Sheard, Thamil Selvee Ramasamy

Mesenchymal stem cells (MSCs) are fibroblast-like cells that give rise to mesenchymal derivatives including bone, fat and cartilage cells. In addition to the bone marrow, they can be readily obtained from adult vascularised peripheral tissues including adipose, olfactory, respiratory tissue, and peripheral blood.

Urine-derived stem cells as innovative platform for drug testing and disease modelling

article

Urine-derived stem cells as innovative platform for drug testing and disease modelling

20 July 2018 | By Audrey Ncube, James Adjaye (Heinrich-Heine-University), Lisa Nguyen, Lucas-Sebastian Spitzhorn, Martina Bohndorf, Shaifur Rahman, Wasco Wruck (Heinrich-Heine-University)

Kidneys are crucial for filtration of drugs and toxins and their proper function is essential for overall health. Unfortunately, due to disease and improper function, kidney transplantation or dialysis are necessary for millions of patients annually all over the world.1,2

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Whitepaper: A guide to achieving better insight with accurate data

17 July 2018 | By IDBS

In today’s modern world, data is everywhere. This eBook will guide you through the steps of how to achieve more with accurate data.

whitepaper

Whitepaper: Opportunities in preclinical development

11 July 2018 | By IDBS

This whitepaper explains how you can find ways to optimise the holistic preclinical development process...

news

CRISPRa used to reprogramme skin cells into pluripotent stem cells

6 July 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have now for the first time succeeded in converting skin cells into pluripotent stem cells by activating the cell's own genes...

news

Stem cells restore function in primate heart-failure study

4 July 2018 | By Dr Zara Kassam (Drug Target Review)

Results suggest an approach that could be tested for treating people with heart failure...

news

CRISPR technology may improve accuracy of predicting heart disease risk

19 June 2018 | By Dr Zara Kassam (Drug Target Review)

Scientists may now be able to predict whether carrying a specific genetic variant increases a person's risk for disease using gene editing and stem cell technologies...

article

Expert view: It’s an exciting time for the use of stem cells in research and the treatment of human disease

8 June 2018 | By Dan Appledorn (Director of US Biology - Essen Bioscience)

The Nobel Prize-winning observations and discoveries of John B. Gurdon and Shinya Yamanaka have ignited an explosion of excitement around the potential use of stem cells in research and treatment of human disease.

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Stem Cells