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A new Cas13 RNA screen has been used to establish guide RNAs for the COVID-19 coronavirus and human RNA segments which could be used in vaccines, therapeutics and diagnostics.
A study has shown that altering amino acid residues in Cas9 to produce new variants can produce a vector with increased gene editing specificity.
Researchers have demonstrated how the drug known as remdesivir works, presenting the viral RNA polymerase of coronaviruses as a target for these conditions.
A rare form of childhood epilepsy could be improved with a therapy called antisense oligonucleotide, following the development of a new model.
A collaboration of academic institutions in the United States has identified a gene that is linked to alternative splicing changes that occur in several cancers.
A key modifier has been identified by researchers in a large fruit fly genetic deletion related to neurodevelopmental disorders such as schizophrenia and autism.
Research has shown that human metapneumovirus uses RNA methylation to hide from the immune system and that knocking out this methylation creates a mutant strain which acts like a vaccine.
A study has shown that long non-coding RNA called DIRC3 can block melanoma growth and could be used to identify new targets for skin cancer therapies.
An mRNA vaccine has been developed which has elicited strong immune responses in mice in the presence of maternal antibodies.
Modern day oncology therapies have seen significant innovation in the last decade. It is high time we commit to using biomarkers that are driven by rational design and the latest computational methods.
Scientists have used nanotechnology to transform healthy immune cells into a drug with enhanced power to kill bacteria to help the immune system fight sepsis.
A new drug-like compound has been developed which reportedly prevents the body from producing a protein that is often at the root of Parkinson's disease.
In a pre-clinical model of multiple sclerosis, orally treating susceptible mice with a microRNA from the diseased gut has prevented the disease.
A team of researchers has uncovered the structure of a T-box regulatory mechanism in bacteria, which could aid in the development of novel antibiotics.
A study has revealed the structure of an enzyme that promotes cancer growth by mutating RNA, which could be used in the development of cancer treatments.
