news Drugs that trigger immune system alarm could lead to new HIV therapies 5 February 2021 | By Victoria Rees (Drug Target Review) Researchers have suggested that dormant HIV can be eradicated from cells by attacking it based on its viral activities.
news New COVID-19 vaccine elicits strong protective immunity in mice and monkeys 5 February 2021 | By Victoria Rees (Drug Target Review) A new MVA-based vaccine has shown success at inducing COVID-19 antibody and T-cell responses in pre-clinical studies.
news Study provides insight into muscle wasting in cancer patients 4 February 2021 | By Victoria Rees (Drug Target Review) Using a mouse model, researchers found that cancer progression led to fewer skeletal muscle ribosomes, likely explaining muscle wasting.
news Deletions in SARS-CoV-2 Spike protein drive antibody escape, study shows 4 February 2021 | By Victoria Rees (Drug Target Review) Researchers have found that SARS-CoV-2 evades immune responses by deleting parts of its genetic sequence that encode for the Spike protein.
news Majority retain COVID-19 antibodies for six months after infection 3 February 2021 | By Victoria Rees (Drug Target Review) A study has shown that 88 percent of people infected by COVID-19 were able to produce SARS-CoV-2 antibodies after six months.
news Thapsigargin could be used as antiviral to treat COVID-19, study shows 3 February 2021 | By Victoria Rees (Drug Target Review) Researchers have discovered that thapsigargin has novel antiviral properties and is effective against COVID-19 in pre-clinical studies.
news Stem cell study illuminates cause of dilated cardiomyopathy (DCM) 2 February 2021 | By Victoria Rees (Drug Target Review) A study using stem cells has revealed that DCM-causing mutations in LMNA disrupt the organisation of DNA in the nucleus of heart muscle cells.
article Preventing stem cells from transforming into pre-leukaemia stem cells 1 February 2021 | By Victoria Rees (Drug Target Review) Researchers have discovered that two enzymes called APOBEC3C and ADAR1 work together to fuel the transition from pre-cancer stem cells to cancer stem cells in leukaemia.
news “Organs-on-a-chip” reveal how digestive tract may influence neurological disease 1 February 2021 | By Victoria Rees (Drug Target Review) A team has used their new organs-on-a-chip system to replicate the interactions between the brain, liver and colon.
news New ion trap used to create highly accurate mass spectrometer 29 January 2021 | By Victoria Rees (Drug Target Review) Researchers have developed a new mass spectrometer that uses rotation frequencies of ionised molecules to measure mass with high accuracy.
news T cells target broad range of SARS-CoV-2 epitopes, study shows 29 January 2021 | By Victoria Rees (Drug Target Review) A study has found that T cells combat SARS-CoV-2 by targeting many sites on the coronavirus, not just the Spike protein.
news Scientists discover new promising target for diabetes treatment 28 January 2021 | By Victoria Rees (Drug Target Review) Researchers have found a druggable insulin inhibitory receptor named inceptor that could provide a drug target for diabetes.
news Novel compound named BC1618 could serve as new diabetes drug 27 January 2021 | By Victoria Rees (Drug Target Review) Researchers have identified a new compound that improved responses to insulin and treated diabetes in obese mouse models.
news Two novel molecules to potentially combat asthma discovered 26 January 2021 | By Victoria Rees (Drug Target Review) Researchers have discovered that giving L-tyrosine and PCS to mice prevents lung inflammation and an allergic asthma response.
news Researchers uncover insights into pioneer transcription factors 25 January 2021 | By Victoria Rees (Drug Target Review) A research team has discovered how proteins called pioneer transcription factors turn on vital genes in cells.
