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Charles River Laboratories announces extended relationship with The Michael J. Fox Foundation
Extension includes new project to phenotype Parkinson’s disease models and the continuation of LRRK2 research.
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Proteomics
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IL1RAP protein boosts multiple oncogenic pathways in AML
Researchers have discovered that a signalling protein elevated in patients with AML plays a much wider role in the disease than previously thought...
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Researchers uncover up to 100 potential drug targets for cancer
In a new study based on mouse cells, researchers have identified several new potential targets using state-of-the-art technology, many of which could be employed for future treatment of different types of cancers and diseases.
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UFD1 protein responsible for aggressive leukaemia
Researchers have identified a protein critical for the aggressiveness of T-cell leukaemia...
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Antibodies protect nerve-muscle connections in Lou Gehrig’s disease
A study identifies a novel treatment strategy that preserved neuromuscular synapses in a mouse model of aggressive ALS...
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Psoriasis treated with compound derived from immune cells
A compound may be effective against other autoimmune diseases, mouse study shows...
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New study discovers cancer-relevant protein shield
Researchers have uncovered a new protein shield that aids in repairing damaged DNA in cells and affects resistance to drugs used for breast cancer treatment...
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How the study of lipidomics is benefiting from recent advances in mass spectrometry
There are no short-cuts in the complex field of lipidomics, explains Cristina Legido-Quigley, a Principal Investigator in Systems Medicine at Steno Diabetes Center Copenhagen in Denmark and at King’s College London.
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A novel pathway to regulate B cell activity and prevent autoimmunity
Researchers at the Medical University of South Carolina (MUSC) have identified a novel checkpoint of peripheral tolerance, specifically in B cells.
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IPSE protein has potential to alleviate debilitating disease
Chemotherapy-induced hemorrhagic cystitis alleviated by a protein that parasites use to keep hosts alive...
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Study changes long-held concepts of cell decoding
NIH scientists discover macromolecular complexes that could enable medication development...
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Scientists discover new causes of cellular decline in prematurely aging children
Researchers have uncovered new answers about why cells rapidly age in children with the rare and fatal disease, Hutchinson-Gilford Progeria Syndrome (HGPS).
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PARK14 protein associated with inflammation in Parkinson’s
Study overturns previous ideas about enzyme linked to many illnesses
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Turning off autophagy helps chemotherapy stress cancer cells to death
A study has pinpointed a molecule that links autophagy and apoptosis, namely a transcription factor called FOXO3a.
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Modified PIP protein differentiates between cancerous and non-cancerous cells
A discovery sheds light on how cancerous cells differ from healthy ones and could lead to the development of new strategies for therapeutic intervention for difficult-to-treat cancers...
