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Novel peptide therapy improves COVID-19 survival by LEAPS and bounds in mice
Researchers report that their LEAPS COV-19 peptides significantly improved survival in a murine model of COVID-19.
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Peptide therapeutics
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Researchers use somatostatin to treat Alzheimer’s in mice
A team fused the peptide somatostatin to a brain transport protein and found it treated memory loss associated with Alzheimer's in mice.
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CBD could treat inflammation caused by COVID-19, study shows
Researchers have found that CBD reduces inflammation in the lungs of COVID-19 mouse models by increasing levels of the apelin peptide.
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Study reveals 10 SARS-CoV-2 epitopes that could be targeted by antibodies
An analysis of SARS-CoV-2 has allowed researchers to identify epitopes recognised by a large fraction of COVID-19 patients, with 10 that could be targeted by antibodies.
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Researchers identify drug target for treatment of malabsorption in babies
Scientists have found a hormone peptide called YY that presents a promising drug target for malabsorption in babies.
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Exploring the intra-protein non-covalent interactions in the S1 domain of the SARS-CoV-2 S1 Spike protein
The Spike (S) protein is a promising drug target in the quest to develop vaccines and antivirals for SARS-CoV-2 to treat and prevent COVID-19. Intra-protein interaction energy landscape mapping efforts have recently identified key interactions that may be crucial for the S protein’s ability to bind to receptor proteins on…
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Potential COVID-19 treatment and vaccine combination shows success in cells
A possible treatment and vaccine combination for COVID-19 has shown positive results in pre-clinical studies using human cells.
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Novel antiplatelet drug is effective at treating heart attacks in mice, say researchers
The novel nanoparticle delivered Mp6 peptide was able to inhibit thrombosis and reduce inflammation without increasing the risk of bleeding in mice after heart attacks.
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Expert view: GenScript’s unique four-tier platform for successful synthesis of challenging neoantigen peptides for precision medicine
Despite hundreds of off-the-shelf treatments, cancer remains the second leading cause of death globally.
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Novel antibiotic peptide fights ‘superbug’ lung infections in mice
Scientists have developed a new antimicrobial peptide therapy named D8 with high efficacy and low toxicity in mice which could be used to fight lung infections.
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Natural peptides versus COVID-19
Peptides could serve as a potential platform for development of novel drugs for the treatment of the COVID-19 coronavirus.
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Collaboration initiated to develop COVID-19 immunotherapy
The University of Georgia and CEL-SCI Corporation have partnered to develop an immunotherapy to combat the COVID-19 coronavirus using the Ligand Antigen Epitope Presentation System (LEAPS) technology.
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CAR T-cell receptors based on scorpion venom show efficacy in mice
Combining the chlorotoxin peptide with conventional CAR structures, researchers have created a new CAR T cell therapy that has successfully combatted glioblastomas in mice.
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D6PV peptide lowers triglycerides in mouse bloodstream, shows study
Researchers have used a peptide called D6PV to lower triglycerides in mouse models, which could be used as a therapy for high triglyceride-induced acute pancreatitis in humans.
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Diabetes-related proteins examined for the first time at high resolution
A key receptor has been examined for the first time at high resolution which could lead to better treatments for conditions such as type 2 diabetes.
