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Oncology is a branch of medicine that deals with the prevention, diagnosis and treatment of cancer.
18 February 2016 | By Victoria White
The results demonstrate that suppression of NR2F6 in T-cells results in increased expression of key immune stimulatory proteins IL-17 and IL-18...
16 February 2016 | By Victoria White
In one study, the engineered T-cells induced complete remission in 94% of patients with acute lymphoblastic leukaemia...
12 February 2016 | By Victoria White
Scientists tested nimbolide, natural extract derived from India's neem tree, against pancreatic cancer in cell lines and mice...
Antibody-based targeting of vascular endothelial growth factor (VEGF) is a highly successful and widely-used clinical treatment for angiogenesis-related diseases. Currently, bevacizumab (Avastin; Genentech) and ranibizumab (Lucentis; Genentech/Roche) are the leading antibody drugs for targeting VEGF...
8 February 2016 | By Victoria White
Peptidyl arginine deiminase 4 (PAD4) is a protein that plays a role in the development of inflammatory diseases like arthritis...
5 February 2016 | By Victoria White
New research suggests that drugs to prevent, rather than encourage, cell death might be effective at fighting cancer - contrary to how many of the current chemotherapy drugs work...
3 February 2016 | By Victoria White
XMT-1522 is an investigational, Fleximer-based ADC therapy that targets HER2-expressing tumours, including breast, gastric and non-small cell lung cancers...
3 February 2016 | By Victoria White
A new ‘roadmap’ document published today outlines how The London Cancer Hub will become a world-leading life-science campus...
3 February 2016 | By Victoria White
The enhanced agreement will accelerate Adaptimmune’s lead clinical cancer programme, an affinity enhanced T-cell immunotherapy targeting NY-ESO-1...
2 February 2016 | By Victoria White
The £60 million enables the company to maximise the potential of its DUB platform and advance a series of DUB inhibitors...
29 January 2016 | By Victoria White
Researchers have identified the cells that likely give rise to the brain tumour subtype Group 4 medulloblastoma, removing a barrier to developing more effective targeted therapies....
29 January 2016 | By SMi Group
Registration now live for the 5th annual ADC Summit taking place at the Holiday Inn Kensington Forum, London, UK on the 23rd – 24th May 2016...
29 January 2016 | By Victoria White
The lab headed by Thomas Helleday at Karolinska Institutet and Biovica are to collaborate to improve evaluation of new, promising cancer therapies...
28 January 2016 | By Victoria White, Digital Content Producer, Drug Target Review
2015 was an exciting year for the drug discovery industry. Here we look at a selection of stories that particularly stood out for us…
27 January 2016 | By Victoria White
Myeloma UK and the SGC have entered into an open-access research partnership to discover drug targets for myeloma using structural biology and chemical proteomics...
