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Thalamus revealed as key area to target for certain brain disorders
Research shows that cells gather more data inside the thalamus than once believed, potentially changing medicines for brain disorders.
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Neurosciences
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Farnesol shows potential to prevent and treat Parkinson’s disease
Researchers have added to evidence that farnesol prevents and reverses brain damage linked to Parkinson’s disease in mouse models.
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Genetic treatment reverses age-related memory loss in mice
Scientists have shown that manipulating the perineuronal nets (PNNs) in the brains of mice led to the reversal of age-related memory loss.
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Non-invasive optical method could provide insight into brain diseases
A non-invasive, label-free optical method can produce high-resolution imaging of cellular brain diseases in vivo.
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Metal-based molecule could inhibit build-up of Alzheimer’s peptides
UK researchers have created a metal-based molecule that inhibits the build-up of Alzheimer’s-associated peptide, amyloid-β, in lab tests.
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Defective proteins found to be potential targets for Alzheimer’s treatments
US researchers have identified potential new treatment targets for Alzheimer’s disease, as well as existing drugs that could be used against these targets.
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Nanosized molecules inhibit formation of plaques related to Alzheimer’s
In brain tissues, researchers have shown that two different nanosized polyoxoniobate molecules can inhibit the assembly of amyloid plaques.
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Synthetic antibody treats congenital myasthenia in mice
Researchers have designed an antibody that attaches to MuSK, which prevented early lethality of mice with congenital myasthenia.
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Study provides clues to cause and possible treatment of Parkinson’s
Researchers have shown that the leakage of mitochondrial double-stranded DNA into the cell can contribute to Parkinson's disease.
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Drug target to halt progression of Parkinson’s disease identified
Scientists have shown that trapped LC3B protein in brain cells enables Parkinson's disease to spread, presenting a drug target.
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Gene therapy in Alzheimer’s mouse model preserves learning and memory
A new gene therapy that introduced SynCav1 to the brains of Alzheimer's mouse models was shown to preserve neuronal and synaptic plasticity.
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New label-free imaging method created to visualise brain samples
A novel sensitive label-free imaging method has been developed to visualise brain samples using an FxClear-based tissue clearing technique.
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Experimental drug shown to reverse effects of Alzheimer’s in mice
Oral doses of a new drug named CA administered to mouse models led to improvements in Alzheimer's disease, including memory.
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Stem cell therapy repairs damage from dementia in mouse brains
Researchers have developed a stem cell therapy that could treat the damage caused by dementia by launching a repair response.
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Reduced levels of H2S in rat brains protects against dementia
A study has shown that treatments to reduce levels of hydrogen sulphide (H2S) in the brain may help to prevent dementia.
