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Mitochondrial DNA (mtDNA) mutations cause severe disorders that are untreatable and mostly affect the nervous system. The difficulty in funding therapies may also be explained by the lack of viable modelling systems...
A new probe has the potential to help surgeons visualise primary non-fluorescing, low-grade gliomas during surgery to remove the tumour.
Researchers have found that amyloid-? facilitates the interaction between the plaques and abnormal tau.
By using functional MRI researchers have found that neurofeedback training has the potential to reduce the severity of tinnitus or even eliminate it...
Researchers have discovered new mechanisms of cell death, which may be involved in debilitating neurodegenerative disorders...
Charles River Laboratories International, Inc. announced that its team of neuroscience drug discovery experts is presenting 27 scientific posters, both independently and collaboratively with clients, at Neuroscience 2017, the 47th annual meeting of the Society for Neuroscience (SfN).
Researchers have discovered that impairing a critical partnership between brain cells can lead to neurodegeneration...
Drug Target Review welcomes Janusz Kulagowski to its advisory board ...
Flow cytometry continues to evolve at a fast pace and provides neuroscientists with the ability to perform many highly-specialised assays simultaneously. It meets the demands of cutting-edge research in neuroscience that has allowed researchers to isolate particular neural cells from heterogeneous population and catalogue its molecular or physical features...
A team of scientists have discovered what they say is a powerful pain reliever that acts on a previously unknown pain pathway...
Metrion Biosciences Limited and LifeArc, today announced an extension of their existing partnership...
New research in suggests that the protein Efr3a regulates the BDNF-TrkB signaling pathway, which plays an important role in regulating learning and memory...
Draper's Joe Charest explains how synthetic organoids can lead to safer drug testing, and why organ-on-a-chip technology is the future of drug discovery...
In a Phase I clinical trial, heart failure patients treated with patches made from their muscle cells showed improved exercise capacity and heart function after one year. Stem cell patch-based therapy may be a viable heart failure therapy and should be validated in larger clinical trials, researchers conclude.
10 March 2017 | By Charles River
This webinar explores neurological ion channel therapeutic and liability targets, featuring four subtypes of NMDA receptors. We also discuss the rationale and options for assessment of therapeutic compounds on panels of CNS ion channels for evaluating their risk for CNS liabilities...
