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New role unlocked for nervous system in regeneration
Using a computational model, researchers were able to explain, predict, and manipulate the regeneration of a flatworm body.
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Neurons
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New technology to produce dorsal cortical neurons using iPS
Scientists expect that it will soon be possible to treat brain diseases by restoring damaged areas in the brain by mass producing neurons using stem cells...
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BDNF–VEGF interplay key to rapid antidepressant actions
A study reveals a complex interplay of two different growth factors in the rapid and long-lasting antidepressant effects of ketamine...
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Nuclear tracers help assess new drugs for neurodegenerative diseases
New nuclear medicine tracers could help medical researchers find a cure for Alzheimer's and other neurodegenerative diseases.
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Application note: GABAA Receptors
SB Drug Discovery shows the validation of fluorescence and automated electrophysiology assays designed to assess agonists, antagonists and allosteric modulators of these receptors, culminating in a high-throughput electrophysiology assay suited to assessing multiple GABAA receptor subtypes on a single assay plate.
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Compounds in coffee may fight Parkinson’s
Caffeine plus another compound in coffee beans' waxy coating may protect against brain degeneration...
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MRI scans shows promise in predicting dementia
Brain changes evident in scans before memory, cognitive decline...
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New information on the pathological mechanisms of Alzheimer’s disease
Researchers have indicated that the accumulation of pathological tau triggers a safety valve mechanism in the otherwise well-regulated cell membranes...
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Inhibiting USP13 destroys toxic clumps seen in Parkinson’s disease
A team of neurologists have found that one reason Lewy bodies develop is that a molecule, USP13, has removed all the "tags" placed on alpha-synuclein that mark the protein for destruction...
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Sensory neurons can be used to discover therapies for ALS
New approach for testing for ALS may be useful to reverse debilitating disease...
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Brain activity pattern may be early sign of schizophrenia
In a study that might enable earlier diagnosis, neuroscientists find abnormal brain connections that can predict the onset of psychotic episodes...
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GFAP gene mutation creates tangles in brain cells – cause of neurological disease
A recent study in the U.S. has identified how a mutation in the GFAP gene, which encodes for the GFAP protein, causes the tangles in brain cells associated with Alexander disease and may also impact other neurological diseases.
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Laser-capture RNA seq technique connects Parkinson’s and psychiatric diseases
A comprehensive study reveals an expanding universe of 'darkest of the dark matter' RNAs in dopamine-producing cells in our brains...
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Neurons in the inner ear can lead to new therapies for hearing disorders
Researchers have identified four types of neurons in the peripheral auditory system, three of which are new to science...
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Short protein fibres predict the onset and course of Huntington’s disease
A research team has reported that short protein fibres precede the formation of larger deposits that accumulate in the brains of those affected by the incurable Huntington's disease...
