news Groundbreaking data tool may uncover novel class of GPCRs 27 October 2021 | By Anna Begley (Drug Target Review) A new computer-aided tool maps allosteric sites in G protein-coupled receptors to search for allosteric drugs to treat a range of diseases.
news New AI technology could shape the future of RNA therapeutics 27 September 2021 | By Anna Begley (Drug Target Review) Artificial intelligence was shown to predict the 3D shapes of RNA molecules, which could significantly advance RNA therapeutics.
news IL13Ra2 revealed as target against breast cancer-related brain metastasis 21 September 2021 | By Anna Begley (Drug Target Review) Interleukin 13 receptor alpha 2 was found in increased rates in cancer cells that metastasised to the brain and lungs, a new study has shown.
news Researchers simulate hepatitis B infection using computational method 8 September 2021 | By Anna Begley (Drug Target Review) The new study modelled the process of capsid disassembly of the hepatitis B virus at an atomic level to help develop targeted therapies.
news GRP78 molecular chaperone revealed as drug target for COVID-19 25 May 2021 | By Victoria Rees (Drug Target Review) Using computer modelling, a team has shown that a molecular chaperone called GRP78 could be targeted by drugs in strategies to treat COVID-19.
news Fragment screening used to identify potential SARS-CoV-2 antivirals 15 April 2021 | By Victoria Rees (Drug Target Review) Researchers have used fragment screening alongside computational docking to reveal 20 hit antiviral compounds against SARS-CoV-2.
news COVID-19 viral envelope simulation under development 25 March 2020 | By Hannah Balfour (Drug Target Review) Researchers are working to build a complete, all-atom model of the exterior of the coronavirus to aid in drug design.
article Where could bioengineering and technological advances take drug discovery? 19 March 2020 | By Hannah Balfour (Drug Target Review) Drug Target Review explores the findings of a recent review of molecular, cellular, multi-cellular and tissue engineering and modelling technologies for drug design.
news Novel technique creates complex synthetic drug molecules 18 February 2020 | By Victoria Rees (Drug Target Review) A new method has been developed by researchers to create synthetic molecules which replicate natural structures and have potential medicinal uses.
news Carbon hydrogen functionalisation could provide new route for synthesising compounds 12 February 2020 | By Victoria Rees (Drug Target Review) The carbon hydrogen functionalisation process could be used to make 3D scaffolds for pharmaceutical compounds, say researchers.
news Richard Goodwin joins DTR Advisory Board 11 October 2017 | By Steve Bremer (Drug Target Review) Dr Goodwin is the latest top-level scientist to join DTR's advisory board
news How receptors for medicines work inside cells 6 September 2017 | By Dr Zara Kassam (Drug Target Review) G protein-coupled receptors are the key target of a large number of drugs, scientists have now been able to show more precisely how these receptors act in the cell interior...
news Flexible new method for early cancer diagnosis 25 May 2017 | By Niamh Marriott (Drug Target Review) Investments are now being made to roll out this innovation across healthcare and broaden the scope of the research in this field.
news DFG €66 million funding for 15 new research training groups 22 May 2017 | By Niamh Marriott (Drug Target Review) The Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) is establishing 15 new Research Training Groups to further support early research...
news Researchers find key molecule that could lead to new anaemia therapies 17 May 2017 | By Niamh Marriott (Drug Target Review) Researchers find key molecule that could lead to new therapies for anaemia and other iron disorders.
