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A study has shown that a group of cells called adipose B cells can become dysfunctional with age, causing metabolic conditions such as diabetes, which has provided a drug target.
A study has revealed that the mitoNEET protein controls a metabolic and functional gateway on mitochondria, which could provide a drug target for cancer.
New method for computational mass spectrometry will speed up the discovery of natural products that could be used in medicines...
Many bioanalytical labs work with a crowded and siloed set of systems and processes. From part electronic to part paper-based workflows to standalone point-solutions, the result is a lack of insight into data and slower reporting and results handling.
This application note aims to demonstrate the benefits of using orthogonal approaches for studying Staphylococcus aureus biofilms—in particular, their susceptibility to antimicrobial agents...
Researchers show the first example of a base-editing tool to treat a disease in utero in animal models...
As the pace of genetic approaches to combating cancer slows, researchers are focusing on novel approaches to identify and create metabolic liabilities in cells. Cancer cells rewire their metabolism to survive and proliferate rapidly; however, there is no single metabolic phenotype that enables this rewired state.
Metabolomics is the state-of-the-art qualitative or quantitative analysis of metabolites present in biological samples. Since the majority of diseases are associated with metabolic alterations – either as a cause or result of the disease process – metabolomics is increasingly being used in drug and biomarker discovery.
Mitochondrial dysfunction has been widely implicated in the neuronal degeneration in Parkinson’s disease (PD). Mitochondria-targeted protective compounds that prevent or minimise a wide range of mitochondrial defects constitute potential therapeutic strategies in the prevention and treatment of neuronal degeneration in PD.
Uncovered details of a molecular pathway in cancer cells could lead to improved treatment...
In this issue: pharmacological targeting of mitochondrial dysfunction in Parkinson’s disease, the evolving role of three dimensional in-vitro cell culture techniques in drug discovery, and NGS: hunting mysterious ‘Dark Matter Genome’ towards rewriting the rules of genetic diseases.
In a series of experiments, researchers have used an experimental compound to successfully reverse hair loss, hair whitening and skin inflammation...
Study uncovers new potential therapeutic approach for a number of diseases linked to inflammation, including atherosclerosis, aortic stenosis and hepatic steatosis...
Mutations in the protein tau, commonly associated with neurodegenerative disorders, may serve as a novel risk factor for cancer...
Euro Metabolomics 2018 will be a platform to investigate on recent research and advancements that can be useful to the researchers.
