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Two therapeutic targets identified for lung cancer
Salk scientists discover a pair of enzymes that drive non-small-cell lung cancer by promoting inflammation which could inform the development of new therapies.
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Application note: Promega’s ADP-Glo™ assay
This application note discusses how the ADP-Glo™ Kinase assay is a universal, homogeneous, high-throughput screening method that measures kinase activity by quantifying the amount of ADP produced during the kinase reaction.
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Scientists uncover steps to kinase enzyme activation
A new study by the University of Arizona (UA) suggests that revealing all the steps required to activate an enzyme called a protein kinase may help identify new ways to target cancer.
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Elimination of c-Raf kinase induces regression of advanced lung tumours
A study has shown how the elimination of the c-Raf kinase by genetic manipulation causes the regression of Kras oncogene-driven advanced lung tumours...
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Shedding light on the brakes of Akt activity
Changes leading to the hyperactivation of the protein kinase Akt are observed in 50% of all tumours. Understanding Akt’s regulatory mechanisms is therefore essential for developing and improving cancer therapies....
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Inhibiting protein kinase CK2 prevents T cell development, could lead to innovative MS treatment
16 September 2016 | By Niamh Louise Marriott, Digital Content Producer
Inhibition of the protein kinase CK2 results in a blockade of exactly those signal pathways required by TH17 cells in order to evolve...
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New drug could stop Parkinson’s Disease
20 July 2016 | By Niamh Louise Marriott, Digital Content Producer
Scientists discovered an interaction in neurons that contributes to Parkinson's disease, showing how drugs now under development could block the process...
