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Immunology

whitepaper

Whitepaper: Optimised homogenisation for virus studies

11 June 2020 | By Bertin Instruments

Best practices and optimised protocols with Precellys for high throughput sample preparation related to virus studies.

surface of several coronavirus particles

news

Protease inhibitors could be highly effective against SARS-CoV-2

10 June 2020 | By Hannah Balfour (Drug Target Review)

Researchers reveal the main protease (Mpro) of SARS-CoV-2 is highly sensitive to disruption, therefore Mpro inhibitors could be a potential COVID-19 therapeutic.

video

Video: ESHG 2019 conference discussion panel: automated sample preparation

10 June 2020 | By Thermo Fisher Scientfic

A result is only as good as the sample preparation that preceded it.

video

Video: Overview of the KingFisher^TM instruments

10 June 2020 | By Thermo Fisher Scientific

ESHG 2019: Automated sample preparation using magnetic bead technology and KingFisher instruments.

coronavirus particle in the crosshares with 'target locked' written above

news

Computational approach identifies novel COVID-19 vaccine targets

9 June 2020 | By Hannah Balfour (Drug Target Review)

Researchers used computational tools to identify regions of the SARS-CoV-2 virus that could potentially provide a safe and long-term immune response.

whitepaper

Application note: High-throughput pathogen detection using a novel MagMAX kit and OpenArray technology

9 June 2020 | By Thermo Fisher Scientfic

Automated detection and isolation of pathogens for multiple samples types.

video

Video: Isolate Circulating tumor cells using the KingFisher

9 June 2020 | By Thermo Fisher Scientfic

New opportunities for liquid biopsy: At automated workflow for isolating circulating tumor cells using KingFisher instruments.

viruses in orange surrounding blue neurons

news

Researchers find microglia are key to protecting brain from viral infection

8 June 2020 | By Hannah Balfour (Drug Target Review)

The team found microglia and CD8 T cells were vital to protecting neurons from vesicular stomatitis virus (VSV) infection and suggest loss of taste and smell in COVID-19 could be due to a certain mechanism of infection.

whitepaper

Application note: Sensitive detection of viral nucleic acids

8 June 2020 | By Thermo Fisher Scientific

A simple and sensitive method for nucleic acid extraction from virus-containing samples, with a range of viral loads.

whitepaper

Application note: Metagenomic analysis of the human microbiome

8 June 2020 | By Thermo Fisher Scientfic

Isolate high-quality, inhibitor-free DNA and RNA from human stool and other sample types suitable for metagenomics sequencing.

article

Antibodies against viral disease: highlighting technologies behind COVID-19 antibody therapy

4 June 2020 | By Shalom Gurjar (OXGENE)

Amid the rush to develop an effective vaccine against COVID-19, antibody therapy has become a major strategy to ameliorate and treat cases of severe disease. Armed with the capacity to neutralise pathogens and orchestrate the immune system, promising antibody candidates for multiple viral indications, including HIV, continue to emerge. Technology…

Even after a blocked vessel has been opened, immune cells in the brain (green) continue to attack synapses (red) and neurons (magenta) in the memory center of the brain, the hippocampus, for at least 30 days after stroke.

news

Novel complement inhibitor improves ischemic stroke recovery in mice, say researchers

3 June 2020 | By Hannah Balfour (Drug Target Review)

Administering a novel complement protein blocker (B4Crry) alongside reperfusion therapy improved cognitive and motor recovery in a model of ischemic stroke.

news

Researchers identify 27 biomarkers of COVID-19 disease severity

2 June 2020 | By Hannah Balfour (Drug Target Review)

Mass spectrometry revealed biomarkers that could be used as drug targets for developing novel therapeutics or to predict whether a patient with COVID-19 will become severely ill.

man with red coronavirus particles in his lungs

news

Mapping SARS-CoV-2 infection in the airway

2 June 2020 | By Hannah Balfour (Drug Target Review)

Researchers found there is a gradient of SARS-CoV-2 infectivity down the airway and that the severe pneumonia symptoms may be caused by aspiration of oral contents into the lungs.

article

Using scientific literature to aid the development of a safe and effective COVID-19 vaccine

2 June 2020 | By Victoria Rees (Drug Target Review)

Researchers in the US describe how they utilised previously published scientific literature to guide the design of their potential COVID-19 vaccine.

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Immunology