Naphthyridine-Azaquinolone reverses Huntington’s DNA repeats in mouse model
Researchers show Naphthyridine-Azaquinolone (NA) could be a possible future therapy able to slow the progression and improve the symptoms of Huntington’s disease.
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Genomics is the branch of molecular biology concerned with the structure, function, evolution, and mapping of genomes.
Researchers show Naphthyridine-Azaquinolone (NA) could be a possible future therapy able to slow the progression and improve the symptoms of Huntington’s disease.
A new study has revealed how bacterial immune systems can be harmful for their hosts and why they are not found in all bacteria.
The development of an innovative new technology has led researchers to suggest RNA-chromatin interactions may play a role in gene regulation.
A new study has created an atlas of human thymus development, to reveal which genes are needed for the production of specific T cells.
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A rare form of childhood epilepsy could be improved with a therapy called antisense oligonucleotide, following the development of a new model.
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A key modifier has been identified by researchers in a large fruit fly genetic deletion related to neurodevelopmental disorders such as schizophrenia and autism.
Researchers have developed a new CRISPR technique, using a minigene, which was inserted into mouse DNA, resulting in improved liver disease symptoms.
Mice with congenital blindness have shown significant improvement in vision after undergoing a new gene therapy.
Researchers have conducted a genetic screen in mice to discover a family of genes that contributes to the development of Huntington's.
Researchers have used stem cells, CRISPR and gene sequencing technology to create the basis of a new brain cancer model that could offer opportunities for drug discovery.
Research into the role of non-coding DNA in cancer development and progression has identified 30 regions that may contribute to tumour growth, which could be therapeutic targets.
A study suggests there may be common genetic pathways between alcohol use disorder and other addictions, so GWAS identification of affected genes could provide the targets for new therapies.
A genetic analysis has shown that a mutation in the HSD3B1 gene is connected to glucocorticoid treatment resistance in patients with severe asthma.