news
bit.bio raises $103 million in first close of Series B financing
The funding will accelerate clinical development of cell therapies using breakthrough gene engineering technology opti-oxTM.
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Genome editing
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Experimental vaccine a major breakthrough for rheumatoid arthritis
A protein-based vaccine has proven a promising option to prevent rheumatoid arthritis, improving bone quality in animal models.
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Zaki syndrome: the newly uncovered condition and its potential cure
Dubbed 'Zaki syndrome', the condition affects prenatal development of several organs and was identified using whole genome sequencing.
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CRISPR-Cas9-based gene dropout screens: a powerful platform for drug discovery
CRISPR holds great promise in advancing pharmacological research and has fuelled the rapid expansion of using gene-edited cells for drug discovery processes. CRISPR-Cas9 dropout screens have emerged as a useful tool for high-throughput large-scale loss-of-function screens, which seek to identify the relationship between genotype and phenotype. Dr Pushpanathan Muthuirulan, Research…
whitepaper
Application note: Streamlined genome engineering in picodroplets
A picodroplet-based microfluidic method for automating the complete genome-editing workflow. Learn more in this free application note.
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Drug Target Review Synthetic Biology ebook 2021
In this ebook, discover why CRISPR can aid the development of new drugs via loss-of-function screens and how the field of synthetic biology is likely to evolve within the context of health.
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Drug Target Review – Issue 3 2021
In this issue, find articles exploring why CRISPR is useful for high-throughput drug discovery, how targeting telomerase may lead to universal cancer vaccines and a new study to identify therapeutics that can be repurposed against COVID-19. Also included are features on neuroscience, organoids and antibodies.
whitepaper
Cell & Gene Therapy Advancements Whitepaper
Download this whitepaper to discover the latest research and developments in cell and gene therapies via exclusive articles and interviews.
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Gene therapy for Morquio A disease successful in rat model
A novel gene therapy has fully corrected whole-body alterations in a rat model, paving the way for Morquio A therapies.
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Video: Empower your electrophysiology studies using new Axon pCLAMP 11 software
The new features in Clampex 11 software enhance functionality in Protocol Editor, increasing the user's ability to create complex experimental protocols involving many command stimulations.
news
Researchers engineer “mini” CRISPR genome editing system
Stanford researchers have developed a multi-purpose “mini” CRISPR system, called CasMINI, that may be easier to deliver into human cells.
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On-demand webinar: An AI-based approach to phenotypic characterisation of neuronal cells
Evaluation of neurotoxicity effects is an active area of investigation in drug discovery and disease modeling.
news
Genome-editing strategy may become novel Alzheimer’s treatment
Scientists have developed a new strategy using brain-wide genome-editing technology that reduced Alzheimer’s disease pathologies in mice.
whitepaper
Info kit: Metabolomics in pharmaceutical research
Accelerate the discovery process of new drugs and targets with a better understanding of the metabolome and lipidome during drug development.
whitepaper
Application note: High-content phenotypic profiling using the cell painting assay
The cell painting assay uses up to six fluorescent dyes to label and visualize a variety of subcellular structures at the single cell level.
