PI3K signalling pathway revealed as potential drug target for obesity
Researchers have found that the PI3K signalling pathway could be targeted to prevent liptoxicity and combat obesity.
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Researchers have found that the PI3K signalling pathway could be targeted to prevent liptoxicity and combat obesity.
According to the study, the transcription factor IRF4 drives T cell differentiation and immunosuppression in multiple human cancers.
Researchers used flow cytometry to characterise which types of T cells are involved in the immune response to COVID-19 and what they target.
A new study has highlighted the advantages of using flow cytometry for the analysis of neuroimmune cell populations from mouse models.
A new report has said that by 2023, the flow cytometry market will be worth $8.88 billion, partly due to an increase in stem cell research.
A simple co-culture assay that can assess anti-tumour T-cell cytotoxicity via luminescence and flow cytometry has been created.
This whitepaper from Beckman Coulter evaluates the analytical performance of the AQUIOS CL flow cytometer in a multi‑centre study.
The World Health Organization (WHO) identifies leishmaniasis as a neglected tropical disease for which new treatments are vitally needed. Leishmaniasis primarily affects people in South America, East Africa and Asia, especially those weakened by malnutrition and poverty. To help those with this disfiguring and potentially life-threatening parasitic disease, the European…
We have entered a new era of drug discovery where the use of advanced cell models such as multi-cellular co-cultures, stem cells and CRISPR-based screens can lead to the next generation of therapeutics.
Not every step of CAR T-cell manufacturing can be tightly regulated, introducing some significant quality control challenges for companies developing CAR T cancer therapies
Biologics represent a growing class of drugs with indications in oncology, chronic inflammation, and autoimmune diseases.
Immuno-oncology (IO) is increasingly prized as an effective therapy in cancer management.
No tumour prevails on its own. Rather, every tumour needs a community to thrive.
Flow cytometry is a powerful, high-throughput technology that is used to characterise suspensions of single cells or particles.
Flow cytometry is a common technique used to identify different immune cell types in mixed population samples such as peripheral blood or tissue samples.