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A drug target is anything within a living organism to which a drug is directed and/or binds, resulting in a change in its behaviour or function.
Ion channels modulate and control many fundamental physiological processes in various tissues and alterations in their functions give rise to a wide range of pathophysiologies, which makes them important drug targets. Indeed, for decades, drugs modulating ion channel activity have been targeted by the pharmaceutical industry. Historically, however, developing drugs…
15 September 2015 | By IntelliCyt
Identification of antibodies against challenging targets using high throughput multiplex-screening approaches...
15 September 2015 | By Victoria White
Researchers have discovered a new gene, USP19, involved in the muscle wasting syndrome cachexia that could be a good target for drug development...
2 September 2015 | By Victoria White
Nearly all advanced oesophageal cancers harbour genetic mutations that can be targeted with emerging drug therapies, according to a new study...
20 July 2015 | By Victoria White
Cellecta has announced the receipt of Phase I SBIR grant funds from the NIH to further its CRISPR-mediated genome-editing library...
2 July 2015 | By Victoria White
Scientists from The Scripps Research Institute have found that microRNAs plays surprisingly different roles in the formation of memory in animal models...
30 June 2015 | By Victoria White
Scientists have unravelled a key process in the bacterium that causes TB, potentially paving the way for new antibiotics to fight the disease...
Find out about the science behind Affimers - including why Affimers are superior to antibodies and details about our custom Affimer process...
Find out more about the applications of Affimers, including how Affimers can be used in the development of therapeutics...
This video introduces Avacta Life Sciences, part of Avacta Group plc and its flagship product, Affimers - a revolutionary new, engineered alternative to antibodies...
17 June 2015 | By Victoria White
GSK is making a substantial investment to launch the Altius Institute for Biomedical Sciences (Altius), an independent, non-profit research institute...
Protein kinases, a diverse group of cellular enzymes, play fundamental roles in maintaining normal cellular functions such as growth, cell cycle control, proliferation, differentiation, migration, cellular survival and apoptotic induction.
28 April 2015 | By Victoria White
A team at CSHL has published results of experiments that lay bare a previously unknown pathway activated in HER2-positive breast cancer...
23 April 2015 | By Thermo Fisher Scientific
The Thermo Scientific Multidrop Combi is a reagent dispenser offering unrivalled levels of flexibility and performance to meet the requirements of reagent dispensing in pharmaceutical and biotechnology laboratories...
23 April 2015 | By Thermo Fisher Scientific
The Thermo Scientific Varioskan LUX Multimode Microplate Reader is designed for bioscience researchers with a wide variety of needs...
