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Potential targets for treatment of leishmaniasis identified
Brazilian scientists show that parasite's penetration of host cells increases expression of certain microRNAs capable of inhibiting the action of the immune system...
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Drug Targets
A drug target is anything within a living organism to which a drug is directed and/or binds, resulting in a change in its behaviour or function.
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DNA-based Zika vaccine found effective at inducing immune response
A new generation DNA-based Zika vaccine is the first to demonstrate both safety and the ability to elicit an immune response against Zika in humans...
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NRF2 pathway provides new approach to cancer drug discovery
Scientists have developed a promising new strategy for the discovery of novel anti-cancer therapies for non-small-cell lung cancers...
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Scientists develop broad-spectrum inhibitors of influenza virus
Scientists have developed broad-spectrum inhibitors of the influenza virus using artificial peptide molecules...
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Novartis and UC Berkeley collaborate to tackle ‘undruggable’ disease targets
Collaboration aims to unlock difficult drug targets and accelerate the discovery of new medicines in areas such as infectious diseases and cancer...
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Streamlined process opens drug development to a new class of steroids
Researchers have developed a technique to produce synthetic steroids that could pave the way for a cascade of new drug discoveries...
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Potential therapeutic protein inhibitors for Chagas disease
Researchers have used a multi-modal integrated approach to develop potential new anti-Chagas therapies...
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Calcilytics as potential novel therapeutic treatments to halt Alzheimer’s disease
Alzheimer’s disease (AD) is the most prevalent form of dementia.1 The common (>95% of cases) slow-developing form of the ailment is known as late-onset AD (LOAD) or sporadic AD (SAD). The rare (
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New mindset in the search for stroke therapies
Researchers have identified a promising new avenue to explore in the search for stroke treatments...
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Drug may curb female infertility from cancer treatments
An existing drug may protect premenopausal women from life-altering infertility that commonly follows cancer treatments...
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Chemo-boosting drug discovered for leukaemia
Drugs developed to treat heart and blood vessel problems could be used to treat leukaemia...
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Breakthrough for mosquito virus outbreaks
A team of researchers are developing ways to treat debilitating diseases caused by alphaviruses such as Chikungunya and Ross River virus...
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New drug targets for a rare kidney and liver disease
In a joint international study, researchers have collaborated to uncover how mutations in a single gene called PKHD1 lead to symptoms associated with a rare kidney and liver disease...
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Novel imaging approach offers insights into HIV’s lifecycle
Scientists have used a novel live-cell fluorescent imaging system that has allowed them to identify individual particles associated with HIV...
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New genetic analysis reveals early diagnosis for breast cancer
Researchers have shown that catching and treating breast cancer before it spreads is now a realistic goal...
