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Researchers reveal therapeutic target for Influenza A
Researchers show altering the molecular interactions between the flu virus and host genes stunts virus replication...
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Drug Targets
A drug target is anything within a living organism to which a drug is directed and/or binds, resulting in a change in its behaviour or function.
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Researchers uncover new target to stop cancer growth
Researchers have discovered that a protein called Munc13-4 helps cancer cells secrete large numbers of exosomes that stimulate tumour progression...
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Human immune ‘trigger’ map paves way for better treatments
A discovery about how human cells are 'triggered' to undergo an inflammatory type of cell death could have implications for treating cancer, stroke and tissue injury, and immune disorders...
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Mini-ecosystems developed to test a molecules therapeutic effect
Research scientists have solved a major problem in chemistry and drug development by using droplet-sized 'mini-ecosystems to quickly see if a molecule can function as a potential therapeutic...
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Application note: Real-time detection of Gs and Gi Signalling in living cells
Genetically-encoded biosensors from Montana Molecular allow for detection of GPCR signalling...
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Platypus venom inspires potential new diabetes treatments
A metabolic hormone found in the venom and gut of Australia’s iconic platypus will now be investigated for its potential to treat type 2 diabetes...
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LM11A-31 restores some bladder function after spinal cord injury
An experimental drug that blocks abnormal neural communication after spinal cord injury could one day be the key to improving quality of life by improving bladder function...
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HIV vaccine elicits antibodies in animals that neutralise dozens of HIV strains
NIH study results represent a major advance for structure-based HIV vaccine design...
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Bladder cancer model could pave the way for better drug efficacy studies
Researchers have created a tool that may help them to uncover why only a fraction of patients responds to new immune-based treatments...
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SB216763 shows preclinical efficacy in Rett syndrome
Researchers describe how a new drug is able to reduce the symptoms and activate the dormant neurons characteristic of Rett Syndrome...
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Scientists screen molecules for new prostate cancer drugs
Cancer researchers have measured systematically how efficient molecules are at suppressing the activity of a protein associated with prostate and other cancers...
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Targeting cPLA2 may improve the treatment of epilepsy
New findings demonstrate that there may be ways to address blood-brain barrier dysfunction in epilepsy...
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Researchers develop a new method to discover drugs to treat epilepsy
Method uncovers a promising new use for a well-known cancer drug in stopping difficult-to-treat seizures...
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Male contraceptive compound stops sperm without affecting hormones
In preclinical tests, researchers have shown how a new compound can immobilise sperm temporarily without side effects...
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Nanoparticles shown to be effective in treating NSCLC
Non-small cell lung cancer Nanoparticles pass the next stage of development in preclinical tests...
