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Protein mTOR regulated by Src in cancer growth
Researchers at Baylor College of Medicine and Texas Children's Hospital have identified a connection between cancer proteins mTORC1 and Src...
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Drug Discovery
In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which new candidate medications are discovered.
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Application note: Orthogonal approaches for studying bacterial biofilms using photometric detection
This application note aims to demonstrate the benefits of using orthogonal approaches for studying Staphylococcus aureus biofilms—in particular, their susceptibility to antimicrobial agents...
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Therapy for hearing loss using sensory hair cells
Sensory hair cells could be regenerated using a therapy developed from the action of the cells in animals such as birds, fish and frogs...
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Immunotherapy targeting blood protein fibrin
Targeting the fibrin protein could ensure that fibrin leaking through the blood-brain barrier does not cause inflammation or disease in the brain...
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Lassa fever vaccine reveals new test for immunity
A Lassa fever vaccine offers researchers a different way to test for protection, which could aid the development of more potent vaccines...
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Drug target identified in oestrogen receptors
A bridge-like structure in oestrogen has been identified by researchers at Case Western Reserve University School of Medicine as a potential drug target...
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Rutin could be effective in treating snakebites from pit vipers
The action of a venomous snakebite from vipers could be treated using a flavonoid called rutin, an inexpensive plant based compound...
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Vaccine offers complete protection against Ebola virus
Researchers at The Wistar Institute have developed a DNA based vaccine that has offered compete protection against the Ebola virus in preclinical trials...
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Immunotherapy could cure advanced pancreatic cancer
Immunotherapy using 'educated' killer cells could be a potential cure for pancreatic cancer, with researchers eliminating all signs of cancer from mice...
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Early treatment could reverse autistic behaviour in tuberous sclerosis
Scientists may have found a sensitive time period where autism related social deficits could be reversed in tuberous sclerosis...
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Micropeptide molecule restores heart function
A micropeptide molecule that reverses structural and functional changes in the heart could be a promising target for gene therapy...
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Elrig 2018: Drug discovery using small and large molecules
The Drug Target Review team are at Elrig Drug Discovery 2018 in the London ExCel...
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Biodegradable devices speed up nerve regeneration
Researchers have developed an implantable and biodegradable device to aid the regeneration of nerve after damage from accidents and sports injuries...
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Prostate and lung cancers driven by common mechanisms
Lung and prostate small cell carcinomas are driven by common mechanisms, which could lead to the development of one treatment for all small cell cancers...
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RNA-seq of 20,000 cardiac cells reveals heart disease insights
RNA analysis of 20,000 cardiac cells from heart tissue in both ordinary and deceased mice showed an insight to the development of heart disease...
