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New drugs targeting gut microbes may reduce the risk of cardiovascular disease
The new class of drugs are mechanism-based inhibitors which potentially interrupt the gut microbial pathway that produces TMAO...
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Drug Delivery
Drug delivery refers to approaches for transporting a pharmaceutical compound in the body as needed to safely achieve its desired therapeutic effect.
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New drug for ALS ready for clinical trials
Previous studies have suggested that a gene therapy drug may be used to treat ALS...
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BCX7353 shows hope for hereditary angioedema
A new drug has been developed to help prevent attacks of hereditary angioedema and at the same offer patients a convenient administration...
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Blood test predicts the best treatment for prostrate cancer
The study showed that patients testing positive for AR-V7 responded better to taxane-based chemotherapy and negative to hormone-targeted therapy...
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Applications of molecular imaging in drug development
The world of healthcare is rapidly evolving. With an ageing population, comes a significant increase in cancers, metabolic diseases and neurodegenerative disorders. New drug candidates are required; however drug development remains a lengthy and expensive process, with the average timeline now over 10 years and costs continuing to rise...
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Revolutionary eye drops to treat age-related macular degeneration
Scientists are one step closer to developing an eye drop that could revolutionise treatment for age-related macular degeneration (AMD)...
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AIBP injection alleviates chemotherapy pain for months in mice
Protein inhibits inflammatory response underlying chronic pain processing; may provide an alternative to opioids for severe, persistent pain...
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Man-made antibodies show promise in attacking cancer cells in animal models
Molecules called aptamers could form new, safer chemotherapy delivery systems...
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Nanoparticles shown to be effective in treating NSCLC
Non-small cell lung cancer Nanoparticles pass the next stage of development in preclinical tests...
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Programming DNA to deliver cancer drugs
New technology could lead to the development of new cancer therapies...
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Extracellular vesicles could be personalised drug delivery vehicles
Researchers developed an approach and platform to create large amounts of fillable and targeted nanovesicles to deliver drugs to tumours in mice...
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Adaptive Designs in Clinical Trials 2018
In its 10th year, the Adaptive Designs in Clinical Trials conference returns to central London in April 2018...
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The highlights to look forward to at SMi Groups Controlled Release Delivery Conference in March 2018
Our agenda is packed with keynote addresses, expert speakers, informative content and senior figures from within the industry…read on to find out more…
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Using bioinformatics sequence similarities to optimise repurposing activities
A significant amount of selectivity and potency data originating from screening of drug targets is generated each year and deposited in public databases. This can be exploited to accelerate drug discovery, in particular, for a variety of repurposing activities...
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An interview with Bjorg K. Hunter, Device Engineering Manager from GSK ahead of Pre-Filled Syringes Europe 2018
A debate on the impact of PFS regulation at Pre-Filled Syringes 2018...
