news CRISPR used to restore retinal function 14 May 2018 | By Dr Zara Kassam (Drug Target Review) Researchers have developed a new technique to restore retinal function in mice afflicted by a degenerative retinal disease, retinitis pigmentosa...
news Diverse Parkinson’s-related disorders may stem from different strains of same protein 10 May 2018 | By Drug Target Review Researchers found that the type of brain cell afflicted in Parkinson’s-related brain disorders dictates which pathological form of α-synuclein (α-syn) protein becomes the disease culprit.
news CKAP4 biomarker identifies stage I lung cancer 10 May 2018 | By Drug Target Review Scientists in Japan have discovered a promising new biomarker – cytoskeleton-associated protein 4 (CKAP4) – for lung cancer, potentially transforming the way the disease is diagnosed and treated.
news Study provides insight into blood signatures of inflammation 9 May 2018 | By Drug Target Review A new study has identified a pattern of inflammation associated with cardio-metabolic risks...
news Cambinol halts spread of toxic protein associated with Alzheimer’s progression 8 May 2018 | By Dr Zara Kassam (Drug Target Review) Research could help lead to the design of drugs that slow neurodegeneration...
news Controlling immune cell migration as therapy for heart disease 7 May 2018 | By Drug Target Review Researchers in the United States find that the location of the body’s immune cells correlates precisely with their function related to heart disease.
news Lymphatic endothelial cells are found to promote the spread of melanoma 4 May 2018 | By Drug Target Review Scientists have investigated the mechanisms by which the lymphatic endothelial cells modulate metastasis in melanoma, providing new targets for therapy development.
news Scientists find possible autism biomarker in cerebrospinal fluid 3 May 2018 | By Drug Target Review Researchers have found that low vasopressin in the cerebrospinal fluid may be a biomarker for autism...
news FoxM1 gene provides promising target for pulmonary hypertension 2 May 2018 | By Dr Zara Kassam (Drug Target Review) The FoxM1 gene will drive the development of new drugs to reverse a process called vascular remodelling - a key feature in pulmonary hypertension...
news New insights into the origins of mutations in cancer 2 May 2018 | By Drug Target Review Scientists use data from human cancers and C. elegans to understand mutational causes of cancer...
news Lipid accumulation in the brain may be an early sign of Parkinson’s disease 30 April 2018 | By Dr Zara Kassam (Drug Target Review) A collaborative team of researchers has found that elevated levels of certain types of lipids in the brain may be an early sign of Parkinson's...
news Antibodies protect nerve-muscle connections in Lou Gehrig’s disease 26 April 2018 | By Dr Zara Kassam (Drug Target Review) A study identifies a novel treatment strategy that preserved neuromuscular synapses in a mouse model of aggressive ALS...
news New compound shows promise for stroke recovery 24 April 2018 | By Drug Target Review Scientists in the U.S. have reported that an experimental compound appears to improve stroke outcome by reducing the destructive inflammation that can often continue months after a person has suffered the stroke.
news Scientists uncover how HIV evades elimination by the immune system 20 April 2018 | By Drug Target Review A team of scientists from Trinity College Dublin has identified the mechanism that enables HIV to evade the immune system, paving the way for a new curative treatment.
news Antimicrobial therapy can prevent sepsis in pneumonia patients 18 April 2018 | By Dr Zara Kassam (Drug Target Review) Research sheds light on the initial phase of infectious disease and potential for prevention of pneumococcal septicaemia...
