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Disease research

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P2X4 receptor key for delaying the progression of Multiple Sclerosis

23 July 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have identified a receptor in the microglial cells that increases their anti-inflammatory potential in order to reduce the damage in MS...

news

32,000 images of analysed CT scans released for AI development

23 July 2018 | By Drug Target Review

Thousands of images have been released to encourage scientists to develop their analysis of lesions, advocating its use for the development of a new universal lesion detector...

news

Aggressive Th17 cells aggravate Parkinson’s disease

21 July 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers identify Parkinson's disease as a possible autoimmune disease...

news

Breath tests could detect pancreatic cancer

20 July 2018 | By Drug Target Review

Breath tests analysing organic compounds in exhaled breath could be used as a new diagnostic tool for pancreatic cancer...

article

From fibroblasts to medicinal signalling cells: a paradigm shift in translational stem cell research

20 July 2018 | By Darius Widera, Jonathan Sheard, Thamil Selvee Ramasamy

Mesenchymal stem cells (MSCs) are fibroblast-like cells that give rise to mesenchymal derivatives including bone, fat and cartilage cells. In addition to the bone marrow, they can be readily obtained from adult vascularised peripheral tissues including adipose, olfactory, respiratory tissue, and peripheral blood.

Urine-derived stem cells as innovative platform for drug testing and disease modelling

article

Urine-derived stem cells as innovative platform for drug testing and disease modelling

20 July 2018 | By Audrey Ncube, James Adjaye (Heinrich-Heine-University), Lisa Nguyen, Lucas-Sebastian Spitzhorn, Martina Bohndorf, Shaifur Rahman, Wasco Wruck (Heinrich-Heine-University)

Kidneys are crucial for filtration of drugs and toxins and their proper function is essential for overall health. Unfortunately, due to disease and improper function, kidney transplantation or dialysis are necessary for millions of patients annually all over the world.1,2

news

Scientists uncover the role of PRMT5 in the production of myelin-forming cells

19 July 2018 | By Dr Zara Kassam (Drug Target Review)

The discovery is a major step toward understanding the mechanisms of myelin production and the potential for treating certain central nervous system diseases...

news

New 3D ‘nanoscope’ facilitates improved brain imaging for Alzheimer’s research

17 July 2018 | By Drug Target Review

Scientists in the U.S. have developed a powerful imaging tool to more accurately reproduce visuals of the brain and investigate mechanisms that precede Alzheimer’s symptoms.

news

Brain changes responsible for the appetite effects of cannabis identified

17 July 2018 | By Dr Zara Kassam (Drug Target Review)

New research on how cannabis use alters eating behaviour could lead to treatments for appetite loss in chronic illness...

news

Urine tests are important in diagnosing myeloma

16 July 2018 | By Drug Target Review

It may be better to examine the urine and the blood of patients suspected of tumours of the plasma cells...

news

Key role of PI3Ky in Chagas disease described

16 July 2018 | By Drug Target Review

The expression of PI3Ky increases during infection by T.cruzi, providing an essential response controlling the parasite and avoiding inflammation...

news

SPECT Imaging technique illuminates immune status of monkeys with HIV-like virus

16 July 2018 | By Dr Zara Kassam (Drug Target Review)

Approach could improve understanding of immune system recovery in people treated for HIV infection...

news

New target for chronic inflammation in colorectal cancer

13 July 2018 | By Drug Target Review

IGF-1 activated by p38 may be a therapeutic target

news

Malaria vaccine targets PMIF

13 July 2018 | By Drug Target Review

A new malaria vaccine targets the protein PMIF, which is crucial in the life cycle of malaria parasites...

news

Epidemiologists highlight a link between Alzheimer’s and herpes

12 July 2018 | By Dr Zara Kassam (Drug Target Review)

A new commentary by epidemiologists supports the viability of a potential way to reduce the risk of Alzheimer's disease...

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