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Umbilical cord stem cells used for early repair of cleft palate

3 October 2018 | By Drug Target Review

Stem cells harvested from the umbilical cord after birth could lead to a therapy to treat cleft lip and palate without the traditional surgery...

news

Alpaca immune system reveals a potential treatment for cancer

3 October 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have identified camelid nanobodies that are able to block EGF, a protein that is abundant in tumour cells...

news

Cancer immunotherapy researchers win Nobel prize

3 October 2018 | By Iqra Farooq (Drug Target Review)

Researchers from the US and Japan have received the Nobel prize in medicine for their development of cancer immunotherapy using PD-1 and CTLA-4...

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Rare mechanism for ALL to relapse after CAR-T therapy

2 October 2018 | By Iqra Farooq (Drug Target Review)

A single leukemic cell has become resistant to CAR-T therapy after unknowingly engineered with the leukemia-targeting CAR lentivirus...

news

Targets for chronic kidney disease treatment

2 October 2018 | By Iqra Farooq (Drug Target Review)

The DAB2 pathway could be a crucial target in treating CKD, as mouse models show a decrease in DAB2 leads to prevention of the condition...

news

New technique generates brain stem cells more efficiently

2 October 2018 | By Drug Target Review

Scientists in Ohio have developed a more efficient means of creating brain stem cells, specifically oligodendrocyte progenitor cells, or OPCs, which will help facilitate greater understanding of neurological disorders that result from myelin damage.

news

Super-resolution microscopy builds multicolour 3D images from 2D

1 October 2018 | By Iqra Farooq (Drug Target Review)

Researchers have developed a method of exploiting fluorescence in microscopy to generate 3D images of organelles and structures within cells from 2D images...

news

Amazonian plant provides anti-tumour activity

1 October 2018 | By Iqra Farooq (Drug Target Review)

A plant from the Amazonian region of Colombia has shown anti-tumour properties against human liver cancer cells, but not against healthy cells...

news

Cancer vaccine shows promise for HER2-positive cancers

1 October 2018 | By Drug Target Review

Treatment with a HER2-targeted therapeutic cancer vaccine provided clinical benefit to several patients with metastatic HER2-positive cancers...

news

Kidney disease biomarker could help detect COPD

28 September 2018 | By Iqra Farooq (Drug Target Review)

A biomarker usually used with kidney disease, could potentially be used to detect COPD through identifying levels of albuminuria in urine...

news

DNA vaccine shows promise for cancer immunotherapy

28 September 2018 | By Dr Zara Kassam (Drug Target Review)

DNA vaccine optimised to cross-react with several MAGE-A isoforms generates a robust immune response and antitumour activity in a pre-clinical model of melanoma...

news

NIH to build cell atlas of the human body

28 September 2018 | By Iqra Farooq (Drug Target Review)

The NIH's Common Fund programme looks towards building a cell map of all individual cells in the human body to aid the detection of disease...

news

‘Paintable’ chemotherapy for melanoma shrinks tumours

27 September 2018 | By Iqra Farooq (Drug Target Review)

A hydrogel incorporating transfersomes and chemotherapy drugs incorporated with some intravenous medication may be the best treatment for melanoma...

news

KCNB1 may be a root cause of Alzheimer’s disease

27 September 2018 | By Iqra Farooq (Drug Target Review)

Researchers have identified that levels of the protein KCNB1 are increased in Alzheimer's brains, which may cause the increase of amyloid-beta plaques...

news

Developments in EEG brain scans could detect mental disorders early

26 September 2018 | By Iqra Farooq (Drug Target Review)

Researchers at the University of San Francisco have suggested how advances in EEG brain scanners could help to diagnose brain conditions earlier...

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