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Disease research

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Neurons made from skin cells are valid when studying disease

16 January 2019 | By Iqra Farooq (Drug Target Review)

A study has found that using skin cells and transforming them into neurons is a valid approach to study neurodegenerative diseases such as Parkinson's...

news

Potential therapeutic target for ALS revealed

16 January 2019 | By Iqra Farooq (Drug Target Review)

Strathmin2 could be used as a biomarker for amyotrophic lateral sclerosis (ALS), a debilitating condition with no proper diagnostic tests or treatments...

news

CRISPR/Cas9 shown to limit impact of certain parasitic diseases

16 January 2019 | By Drug Target Review

Researchers successfully used CRISPR/Cas9 to limit the impact of schistosomiasis and liver fluke infection...

news

Stopping inflammation using a molecular switch

15 January 2019 | By Iqra Farooq (Drug Target Review)

A component in the ubiquitin system has been described as being able to deactivate the innante immune system and could help to prevent immune conditions...

news

Engineered T-cells promote acceptance of organs after transplant

15 January 2019 | By Iqra Farooq (Drug Target Review)

Controlling coronin 1 in T-cells could lead to the immune system not attacking transplanted organs, but still fighting other infections...

news

Using the SVM method to predict enhancers from tissues and cell lines

14 January 2019 | By Iqra Farooq (Drug Target Review)

A team of researchers have developed a computational bioinformatic method to predict and accurately locate enhancer regions on cell lines.

news

CRISPR repurposed to develop better antibiotics

14 January 2019 | By Iqra Farooq (Drug Target Review)

Mobile-CRISPRi could be used to guide gene expression, in turn control levels of proteins produced, enabling scientists to identify key antibiotic targets...

news

New therapeutic concept controls pathogenic T-cells relevant in MS

14 January 2019 | By Dr Zara Kassam (Drug Target Review)

Researchers have identified an innovative and promising therapeutic option to treat multiple sclerosis...

news

Hidden culprit in heart failure discovered

11 January 2019 | By Drug Target Review

A study has identified that PI3K alpha could be the culprit of heart failure, as it binds to gelsolin, suppressing it and preventing it from working...

news

UCLA researchers correct mutation causing IPEX

11 January 2019 | By Iqra Farooq (Drug Target Review)

A stem cell therapy rectifying the FoxP3 gene has been developed to treat IPEX, and has virtually cleared symptoms of the condition in mice...

Novel classification can lead to new ways to diagnose and treat cancer

news

Ubiquilin-4 biomarker links cancer progression to genome instability

11 January 2019 | By Dr Zara Kassam (Drug Target Review)

High level of specific protein in tumours indicates prognosis as well as optimal treatments...

news

Two-antibody cocktail could treat Ebola in one dose

10 January 2019 | By Drug Target Review

A study has described a two-antibody cocktail medication that has been successful in vivo italics trials and could treat Ebola in one dose...

news

Stem cell study optimises bone marrow transplants

10 January 2019 | By Iqra Farooq (Drug Target Review)

A study has shown how stem cells that are transplanted act in a different way to those ordinarily present, without a transplant...

news

Drug sponge could minimise effects of cancer therapy

9 January 2019 | By Drug Target Review

A drug 'sponge' could be the future method of soaking up excess drugs within the body after cancer treatments such as chemotherapy to prevent side effects...

news

Insights into controlling gene expression

9 January 2019 | By Iqra Farooq (Drug Target Review)

A study has given insight into gene expression and could enable scientists to determine how certain RNAP inhibitors work within the body...

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Disease research