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Disease research

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New label-free microscopy method enables imaging inside living cells

21 April 2020 | By Victoria Rees (Drug Target Review)

By combining quantitative phase microscopy and molecular vibrational imaging, researchers have created a new label-free microscopy technique.

news

Nanobodies developed to image COVID-19 Spike protein

20 April 2020 | By Victoria Rees (Drug Target Review)

Researchers in the UK have selected nanobodies that bind with high affinity to the Spike protein on the COVID-19 coronavirus, enabling stabilisation for imaging.

news

Chemical tool developed to examine lipids in living cells

20 April 2020 | By Victoria Rees (Drug Target Review)

A new method has been developed by researchers using chemical tools activated by light to influence lipid concentration in living cells.

news

UK government funds 21 new research projects into COVID-19

20 April 2020 | By Victoria Rees (Drug Target Review)

A total of 21 COVID-19 research projects have been granted funding by the UK government, including vaccine and therapeutic development.

RNA strand in light blue surrounded by coronavirus particles in darker blue

news

Novel visualisation platform to aid understanding of COVID-19 strain evolution

20 April 2020 | By Hannah Balfour (Drug Target Review)

The visualisation platform is being used to analyse how the SARS-CoV-2 virus causing COVID-19 is evolving and could be used to inform drug design.

head and shoulders photo of an adult cynomolgus macaque

news

Cynomolgus macaques: a promising animal model of COVID-19 infection?

17 April 2020 | By Hannah Balfour (Drug Target Review)

Researchers comparing the effects of SARS-CoV-2, SARS-CoV and MERS-CoV in cynomolgus macaques suggest they could be an effective animal model for testing COVID-19 therapeutics.

news

Specialised proteins could halt cytokine storms in COVID-19 patients

17 April 2020 | By Victoria Rees (Drug Target Review)

Researchers who developed modified proteins say this could be used in the fight against COVID-19, by tackling cytokine storms.

rotavirus particles in pink on a red background

news

VP3 protein: revealing the structure of a potential rotavirus drug target

17 April 2020 | By Hannah Balfour (Drug Target Review)

Researchers hope that by revealing the rotavirus VP3 protein structure and mRNA capping functions, novel antivirals could be designed to prevent or combat rotavirus infections.

news

Severe COVID-19 symptoms may be caused by overactive neutrophils

16 April 2020 | By Hannah Balfour (Drug Target Review)

An international consortium suggest that the severe symptoms of COVID-19, including Acute Respiratory Distress Syndrome (ARDS), could be caused by Neutrophil Extracellular Traps (NETs).

news

Consortia of microbes could reduce inflammation and promote colon health, say researchers

16 April 2020 | By Victoria Rees (Drug Target Review)

A study has shown that two products of bacterial bile metabolism boost the conversion of precursor T cells into peripheral Tregs, which suppress chronic inflammation in the colon.

news

Stem cells in COPD patient lungs revealed as drug target for condition

16 April 2020 | By Victoria Rees (Drug Target Review)

There are heightened levels of abnormal stem cells in the lungs of COPD patients, presenting a drug target that researchers are screening compounds against.

article

The coronavirus as a personalised enemy of mankind

15 April 2020 | By Dr Ulrich Kutschera (University of Kassel)

How has evolution led us to the point where humans are an ideal host for SARS-CoV-2, the virus that causes the COVID-19 coronavirus?

news

Novel 3D imaging technology could improve fluorescence microscopy

15 April 2020 | By Victoria Rees (Drug Target Review)

A new technique called Coded Light-sheet Array Microscopy (CLAM) has been developed by researchers to improve 3D imaging of living specimens.

Cartoon of people of various races/religions/ethnicities all wearing white surgical masks to protect against COVID-19

news

Researchers release 21 openly available SARS-CoV-2 genome sequences

14 April 2020 | By Hannah Balfour (Drug Target Review)

Austrian researchers reveal the first 21 SARS-CoV-2 viral genomes as part of their project to aid in international understanding of how the virus causing COVID-19 mutates.

news

Label-free array system market to be worth $1,600 million by 2025, study finds

14 April 2020 | By Victoria Rees (Drug Target Review)

The global label-free array system market will grow at a compound annual growth rate of 7.44 percent in the forecast period, says new research.

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