news Study shows structure of biocatalysts changes in certain environments 27 April 2020 | By Victoria Rees (Drug Target Review) Researchers have found that the structure of biocatalysts such as enzymes depends on whether they are in cells or in the test tube.
news Novel antibody slows cancer growth and metastasis in mice 27 April 2020 | By Hannah Balfour (Drug Target Review) The antibody targets a cell receptor in blood vessels and slowed breast and lung cancer growth as well as metastasis in murine models.
news Cell types enabling initial COVID-19 infection identified by researchers 27 April 2020 | By Victoria Rees (Drug Target Review) An international group of researchers has revealed that goblet and ciliated cells in the nose have high levels of the entry proteins for the SARS-CoV-2 coronavirus.
news Hyperferritinaemia could be causing severe COVID-19 27 April 2020 | By Hannah Balfour (Drug Target Review) Professor Yehuda Shoenfeld suggests hyperferritinaemia, a condition caused by high ferritin levels, may be causing the severe COVID-19 symptoms.
news Researchers identify drug target to treat cocaine addiction 24 April 2020 | By Victoria Rees (Drug Target Review) Researchers have revealed the importance of dopaminergic control on striatal responses to psychostimulants, suggesting a drug target for cocaine addiction.
news Research focus should remain on high quality studies during COVID-19 pandemic, say scientists 24 April 2020 | By Victoria Rees (Drug Target Review) Exceptions to high quality research should not be made simply because of the COVID-19 pandemic, argue scientists in a new commentary.
news UK organisations call for investigation of ethnicity and COVID-19 incidence and outcome 24 April 2020 | By Hannah Balfour (Drug Target Review) The UK National Institute of Health Research (NIHR) and UK Research and Innovation (UKRI) wish to fund research exploring if people from black, Asian and middle eastern backgrounds are disproportionately at risk from COVID-19.
news Self-aligning smart microscope achieves unprecedented resolution 23 April 2020 | By Hannah Balfour (Drug Target Review) The developers of the ultra-precise single-molecule microscope demonstrated it can resolve interactions between molecules within living cells and is compatible with existing microscopes.
news Fundamental molecular research underpins our ability to combat COVD-19, says article 23 April 2020 | By Hannah Balfour (Drug Target Review) Ali Shilatifard’s article explains how investment in institutes performing molecular research is essential, as it is the foundation for all attempts to combat COVID-19 and other future pandemics.
news Experiments with Marburg virus reveal novel antibody protective mechanisms 22 April 2020 | By Hannah Balfour (Drug Target Review) Researchers discovered the monoclonal antibodies of a convalescent Marburg infection patient bound to the glycoprotein and combatted infection in two novel ways.
news COVID-19 research indicates SARS-CoV-2 exploits immune defences to drive infection 22 April 2020 | By Hannah Balfour (Drug Target Review) A new study has revealed that less than 10 percent of respiratory and intestinal cells are susceptible to SARS-CoV-2 infection and expression of ACE2 receptors is driven by the body's immune response.
news Researchers develop open access database on macrolactones 22 April 2020 | By Victoria Rees (Drug Target Review) A group of researchers has created a free library of 14,000 known macrolactones for other scientists to use in drug development.
news Glycomimetics could prevent COVID-19 from infecting human cells 21 April 2020 | By Hannah Balfour (Drug Target Review) Glycomimetics, a novel class of antivirals, prevented influenza, herpes viruses and papillomaviruses from infecting cells in animal models and could show similar efficacy against COVID-19.
news £280 million donated for COVID-19 research in three months 21 April 2020 | By Victoria Rees (Drug Target Review) A study has shown that the COVID-19 pandemic has resulted in a high level of research donations, making the condition the third most funded disease on average by year.
news High-throughput protocol for producing tetramer assay probes used to investigate COVID-19 21 April 2020 | By Hannah Balfour (Drug Target Review) The developers of a novel method to create immunological assay probes for screening T cells has leveraged their new protocol against COVID-19.
