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New model predicts cognitive decline two years ahead
Researchers hope the system can choose the right patients to enroll in clinical trials, to speed discovery of drug treatments.
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Clinical trials
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New system enables improved pre-clinical testing of heart drugs
Researchers have extended the life of heart segments from 24 hours to six days, enabling pre-clinical trials to experiment on these new models for longer periods of time.
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Treatment for Lafora disease shows promise in pre-clinical study
A novel antibody-enzyme fusion therapeutic strategy for Lafora disease has shown effectiveness in pre-clinical study mice models.
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Models should be in social conditions for pre-clinical trials, study finds
A study has shown that mice and rats become stressed when housed alone, affecting results of pre-clinical trials.
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New version of HIV vaccine could soon be ready for clinical trials
A promising vaccine that clears an HIV-like virus from monkeys is closer to clinical trial human testing.
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Guide: Questions to ask your human biological specimen provider
The foundations for protecting human research subjects come from the ethical principles surrounding the Belmont report : Respect for persons, beneficence, and justice.
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Gene activity app could reduce live model usage
Researchers have developed an app which displays the effects of diseases in mice models and can be accessed globally.
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First patient enrolled in Parkinson’s treatment study
A trial has begun in the US for the ENT-01 therapy treatment of Parkinson’s, with the first patient enrolled.
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Female animals should be included in trials, new argument proposes
Using exclusively male animals in experiments biases results, argues Rebecca Shansky.
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US company put on notice for marketing unapproved stem cell products
Arizona company claims their products can treat Lyme disease, diabetes, Parkinson’s disease and more, but have not been approved for any use.
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UK drug discovery market ‘thriving’ says new report
A new report reveals a thriving service and supply sector for the UK in addition to its research and development biotechs.
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Update on the development of new novel cancer immunotherapy
The SCIB2 vaccine is to to be administered using new nanoparticle formulation in planned Phase 1/2 clinical trial.
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New method could speed up drug development and diminish drug trial fails
A new method of assessing the actions of medicines by matching them to their unique protein receptors could accelerate drug development.
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Genomic analysis identifies potential prostate cancer targets
In a recent study more than half of patients with advanced prostate cancers appear to be strong candidates for targeted cancer therapies.
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WINTHER trial yields promising results
Comprehensive tumour profiling promises new therapeutic options for patients with advanced cancer.
