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An assay is an analytical procedure in laboratory medicine, pharmacology and molecular biology for measuring the activity of a target entity.
1 February 2018 | By PerkinElmer
This webinar discussed a screening assay that recapitulates the activation of ER stress sensor IRE1 and an assay to quantify cell migration phenotypes, as applied to cardiovascular target validation and drug discovery.
Reasons for phenotypic vs. target based drug discovery strategies, challenges of and maximising return of phenotypic assays.
Describing how a single nuclear stain can enable phenotypic profiling for new and additional perspectives on assays at no extra cost.
Water immersion lenses provide: brighter images from HCS samples; faster and gentler imaging; higher quality images from both 2D and 3D samples.
Researchers have developed a single blood test that screens for eight common cancer types and helps identify the location of cancer...
Amplifying patient-specific T cells outside the body could increase the efficiency of cancer immunotherapies...
15 January 2018 | By BMG Labtech GmbH
Optimising the receptor binding kinetics of new drugs can have significant benefits, ranging from improved duration of action to enhanced efficacy through the insurmountable antagonism of dynamic physiological systems.Despite this, the kinetics of new receptor ligands are rarely measured early in the drug discovery process, largely because current assays are…
Large, human cardiac-muscle patches created in the lab have been tested, for the first time, on large animals the patches significantly improved recovery from heart attack injury...
In this application note, PerkinElmer demonstrates the ease and utility of the AlphaScreen® cAMP assay for detecting both agonist and antagonist-induced cAMP responses within cells.
5 January 2018 | By PerkinElmer
LANCE (Lanthanide chelate excite) is a TR-FRET (time-resolved fluorescence resonance energy transfer), homogenous, no wash technology.
In this application note, PerkinElmer demonstrates how LANCE® Ultra, a homogeneous assay format, can be used to quickly and accurately assess modulation of pSTAT3.
In this application note, PerkinElmer demonstrates the ease and utility of using LANCE® Ultra, a homogeneous assay format, for determining binding profiles of therapeutic monoclonal antibodies to FcγRs.
In this application note, PerkinElmer demonstrates the sensitivity, robust performance, and HTS suitability of the LANCE Ultra cytokine biomarker kits.
3 January 2018 | By PerkinElmer
Alpha (Amplified Luminescence Proximity Homogeneous Assay) bead-based technology for no-wash assays.
